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Post-transcriptional gene regulation by MAP kinases via AU-rich elements.
Clark A, Dean J, Tudor C, Saklatvala J. Clark A, et al. Front Biosci (Landmark Ed). 2009 Jan 1;14:847-71. doi: 10.2741/3282. Front Biosci (Landmark Ed). 2009. PMID: 19273104 Review.
Dual-Specificity Phosphatase 1 and Tristetraprolin Cooperate To Regulate Macrophage Responses to Lipopolysaccharide.
Smallie T, Ross EA, Ammit AJ, Cunliffe HE, Tang T, Rosner DR, Ridley ML, Buckley CD, Saklatvala J, Dean JL, Clark AR. Smallie T, et al. Among authors: saklatvala j. J Immunol. 2015 Jul 1;195(1):277-88. doi: 10.4049/jimmunol.1402830. Epub 2015 May 27. J Immunol. 2015. PMID: 26019272 Free PMC article.
Anti-inflammatory effects of selective glucocorticoid receptor modulators are partially dependent on up-regulation of dual specificity phosphatase 1.
Joanny E, Ding Q, Gong L, Kong P, Saklatvala J, Clark AR. Joanny E, et al. Br J Pharmacol. 2012 Feb;165(4b):1124-36. doi: 10.1111/j.1476-5381.2011.01574.x. Br J Pharmacol. 2012. PMID: 21718312 Free PMC article.
Glucocorticoid regulation of mouse and human dual specificity phosphatase 1 (DUSP1) genes: unusual cis-acting elements and unexpected evolutionary divergence.
Tchen CR, Martins JR, Paktiawal N, Perelli R, Saklatvala J, Clark AR. Tchen CR, et al. J Biol Chem. 2010 Jan 22;285(4):2642-52. doi: 10.1074/jbc.M109.037309. Epub 2009 Nov 23. J Biol Chem. 2010. PMID: 19940143 Free PMC article.
MAPKAP kinase 2 blocks tristetraprolin-directed mRNA decay by inhibiting CAF1 deadenylase recruitment.
Marchese FP, Aubareda A, Tudor C, Saklatvala J, Clark AR, Dean JL. Marchese FP, et al. J Biol Chem. 2010 Sep 3;285(36):27590-600. doi: 10.1074/jbc.M110.136473. Epub 2010 Jul 1. J Biol Chem. 2010. PMID: 20595389 Free PMC article.
Dominant Suppression of Inflammation via Targeted Mutation of the mRNA Destabilizing Protein Tristetraprolin.
Ross EA, Smallie T, Ding Q, O'Neil JD, Cunliffe HE, Tang T, Rosner DR, Klevernic I, Morrice NA, Monaco C, Cunningham AF, Buckley CD, Saklatvala J, Dean JL, Clark AR. Ross EA, et al. J Immunol. 2015 Jul 1;195(1):265-76. doi: 10.4049/jimmunol.1402826. Epub 2015 May 22. J Immunol. 2015. PMID: 26002976 Free PMC article.
Src and fibroblast growth factor 2 independently regulate signaling and gene expression induced by experimental injury to intact articular cartilage.
Watt FE, Ismail HM, Didangelos A, Peirce M, Vincent TL, Wait R, Saklatvala J. Watt FE, et al. Arthritis Rheum. 2013 Feb;65(2):397-407. doi: 10.1002/art.37765. Arthritis Rheum. 2013. PMID: 23124605
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