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848 results
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TRIB3 suppresses tumorigenesis by controlling mTORC2/AKT/FOXO signaling.
Salazar M, Lorente M, García-Taboada E, Gómez EP, Dávila D, Zúñiga-García P, Flores JM, Rodríguez A, Hegedus Z, Mosén-Ansorena D, Aransay AM, Hernández-Tiedra S, López-Valero I, Quintanilla M, Sánchez C, Iovanna JL, Dusetti N, Guzmán M, Francis SE, Carracedo A, Kiss-Toth E, Velasco G. Salazar M, et al. Mol Cell Oncol. 2015 Apr 18;2(3):e980134. doi: 10.4161/23723556.2014.980134. eCollection 2015 Jul-Sep. Mol Cell Oncol. 2015. PMID: 27308456 Free PMC article.
Oncosuppressive functions of tribbles pseudokinase 3.
Salazar M, Lorente M, Orea-Soufi A, Dávila D, Erazo T, Lizcano J, Carracedo A, Kiss-Toth E, Velasco G. Salazar M, et al. Biochem Soc Trans. 2015 Oct;43(5):1122-6. doi: 10.1042/BST20150124. Biochem Soc Trans. 2015. PMID: 26517935 Review.
The New Antitumor Drug ABTL0812 Inhibits the Akt/mTORC1 Axis by Upregulating Tribbles-3 Pseudokinase.
Erazo T, Lorente M, López-Plana A, Muñoz-Guardiola P, Fernández-Nogueira P, García-Martínez JA, Bragado P, Fuster G, Salazar M, Espadaler J, Hernández-Losa J, Bayascas JR, Cortal M, Vidal L, Gascón P, Gómez-Ferreria M, Alfón J, Velasco G, Domènech C, Lizcano JM. Erazo T, et al. Among authors: salazar m. Clin Cancer Res. 2016 May 15;22(10):2508-19. doi: 10.1158/1078-0432.CCR-15-1808. Epub 2015 Dec 15. Clin Cancer Res. 2016. PMID: 26671995 Clinical Trial.
AMBRA1 links autophagy to cell proliferation and tumorigenesis by promoting c-Myc dephosphorylation and degradation.
Cianfanelli V, Fuoco C, Lorente M, Salazar M, Quondamatteo F, Gherardini PF, De Zio D, Nazio F, Antonioli M, D'Orazio M, Skobo T, Bordi M, Rohde M, Dalla Valle L, Helmer-Citterich M, Gretzmeier C, Dengjel J, Fimia GM, Piacentini M, Di Bartolomeo S, Velasco G, Cecconi F. Cianfanelli V, et al. Among authors: salazar m. Nat Cell Biol. 2015 Jan;17(1):20-30. doi: 10.1038/ncb3072. Epub 2014 Dec 1. Nat Cell Biol. 2015. PMID: 25438055 Free PMC article.
TRB3 links ER stress to autophagy in cannabinoid anti-tumoral action.
Salazar M, Carracedo A, Salanueva IJ, Hernández-Tiedra S, Egia A, Lorente M, Vázquez P, Torres S, Iovanna JL, Guzmán M, Boya P, Velasco G. Salazar M, et al. Autophagy. 2009 Oct;5(7):1048-9. doi: 10.4161/auto.5.7.9508. Epub 2009 Oct 14. Autophagy. 2009. PMID: 19652543 No abstract available.
848 results