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SHB and angiogenic factors promote ES cell differentiation to insulin-producing cells.
Saldeen J, Kriz V, Agren N, Welsh M. Saldeen J, et al. Biochem Biophys Res Commun. 2006 Jun 2;344(2):517-24. doi: 10.1016/j.bbrc.2006.03.129. Epub 2006 Apr 19. Biochem Biophys Res Commun. 2006. PMID: 16630561
Cytokine-induced apoptosis and necrosis are preceded by disruption of the mitochondrial membrane potential (Deltapsi(m)) in pancreatic RINm5F cells: prevention by Bcl-2.
Barbu A, Welsh N, Saldeen J. Barbu A, et al. Among authors: saldeen j. Mol Cell Endocrinol. 2002 Apr 25;190(1-2):75-82. doi: 10.1016/s0303-7207(02)00009-6. Mol Cell Endocrinol. 2002. PMID: 11997180
The SHB adapter protein is required for normal maturation of mesoderm during in vitro differentiation of embryonic stem cells.
Kriz V, Agren N, Lindholm CK, Lenell S, Saldeen J, Mares J, Welsh M. Kriz V, et al. Among authors: saldeen j. J Biol Chem. 2006 Nov 10;281(45):34484-91. doi: 10.1074/jbc.M604084200. Epub 2006 Sep 12. J Biol Chem. 2006. PMID: 16971391 Free article.
Interdependent fibroblast growth factor and activin A signaling promotes the expression of endodermal genes in differentiating mouse embryonic stem cells expressing Src Homology 2-domain inactive Shb.
Funa NS, Saldeen J, Akerblom B, Welsh M. Funa NS, et al. Among authors: saldeen j. Differentiation. 2008 May;76(5):443-53. doi: 10.1111/j.1432-0436.2007.00249.x. Epub 2007 Dec 17. Differentiation. 2008. PMID: 18093225
The acid sphingomyelinase inhibitor SR33557 counteracts TNF-alpha-mediated potentiation of IL-1beta-induced NF-kappaB activation in the insulin-producing cell line Rinm5F.
Saldeen J, Jaffr├ęzou JP, Welsh N. Saldeen J, et al. Autoimmunity. 2000 Dec;32(4):241-54. doi: 10.3109/08916930008994098. Autoimmunity. 2000. PMID: 11191283
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