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Uncoupling protein-2: evidence for its function as a metabolic regulator.
Saleh MC, Wheeler MB, Chan CB. Saleh MC, et al. Diabetologia. 2002 Feb;45(2):174-87. doi: 10.1007/s00125-001-0737-x. Diabetologia. 2002. PMID: 11935148 Review.
cAMP-mediated signaling normalizes glucose-stimulated insulin secretion in uncoupling protein-2 overexpressing beta-cells.
McQuaid TS, Saleh MC, Joseph JW, Gyulkhandanyan A, Manning-Fox JE, MacLellan JD, Wheeler MB, Chan CB. McQuaid TS, et al. J Endocrinol. 2006 Sep;190(3):669-80. doi: 10.1677/joe.1.06723. J Endocrinol. 2006. PMID: 17003268
Uncoupling protein 2 and islet function.
Chan CB, Saleh MC, Koshkin V, Wheeler MB. Chan CB, et al. Diabetes. 2004 Feb;53 Suppl 1:S136-42. doi: 10.2337/diabetes.53.2007.s136. Diabetes. 2004. PMID: 14749279 Review.
Free fatty acid-induced beta-cell defects are dependent on uncoupling protein 2 expression.
Joseph JW, Koshkin V, Saleh MC, Sivitz WI, Zhang CY, Lowell BB, Chan CB, Wheeler MB. Joseph JW, et al. J Biol Chem. 2004 Dec 3;279(49):51049-56. doi: 10.1074/jbc.M409189200. Epub 2004 Sep 23. J Biol Chem. 2004. PMID: 15448158
Mutated ATP synthase induces oxidative stress and impaired insulin secretion in beta-cells of female BHE/cdb rats.
Saleh MC, Fatehi-Hassanabad Z, Wang R, Nino-Fong R, Wadowska DW, Wright GM, Harper ME, Chan CB. Saleh MC, et al. Diabetes Metab Res Rev. 2008 Jul-Aug;24(5):392-403. doi: 10.1002/dmrr.819. Diabetes Metab Res Rev. 2008. PMID: 18273840
Inhibition of Kv2.1 voltage-dependent K+ channels in pancreatic beta-cells enhances glucose-dependent insulin secretion.
MacDonald PE, Sewing S, Wang J, Joseph JW, Smukler SR, Sakellaropoulos G, Wang J, Saleh MC, Chan CB, Tsushima RG, Salapatek AM, Wheeler MB. MacDonald PE, et al. J Biol Chem. 2002 Nov 22;277(47):44938-45. doi: 10.1074/jbc.M205532200. Epub 2002 Sep 20. J Biol Chem. 2002. PMID: 12270920
Guanosine protects against reperfusion injury in rat brains after ischemic stroke.
Connell BJ, Di Iorio P, Sayeed I, Ballerini P, Saleh MC, Giuliani P, Saleh TM, Rathbone MP, Su C, Jiang S. Connell BJ, et al. J Neurosci Res. 2013 Feb;91(2):262-72. doi: 10.1002/jnr.23156. Epub 2012 Nov 14. J Neurosci Res. 2013. PMID: 23151946
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