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47 results
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Control of beta-catenin stability: reconstitution of the cytoplasmic steps of the wnt pathway in Xenopus egg extracts.
Salic A, Lee E, Mayer L, Kirschner MW. Salic A, et al. Mol Cell. 2000 Mar;5(3):523-32. doi: 10.1016/s1097-2765(00)80446-3. Mol Cell. 2000. PMID: 10882137
A biochemical screen for identification of small-molecule regulators of the Wnt pathway using Xenopus egg extracts.
Thorne CA, Lafleur B, Lewis M, Hanson AJ, Jernigan KK, Weaver DC, Huppert KA, Chen TW, Wichaidit C, Cselenyi CS, Tahinci E, Meyers KC, Waskow E, Orton D, Salic A, Lee LA, Robbins DJ, Huppert SS, Lee E. Thorne CA, et al. Among authors: salic a. J Biomol Screen. 2011 Oct;16(9):995-1006. doi: 10.1177/1087057111416657. Epub 2011 Aug 21. J Biomol Screen. 2011. PMID: 21859680 Free PMC article.
Small-molecule inhibition of Wnt signaling through activation of casein kinase 1α.
Thorne CA, Hanson AJ, Schneider J, Tahinci E, Orton D, Cselenyi CS, Jernigan KK, Meyers KC, Hang BI, Waterson AG, Kim K, Melancon B, Ghidu VP, Sulikowski GA, LaFleur B, Salic A, Lee LA, Miller DM 3rd, Lee E. Thorne CA, et al. Among authors: salic a. Nat Chem Biol. 2010 Nov;6(11):829-36. doi: 10.1038/nchembio.453. Epub 2010 Oct 3. Nat Chem Biol. 2010. PMID: 20890287 Free PMC article.
Lrp6 is required for convergent extension during Xenopus gastrulation.
Tahinci E, Thorne CA, Franklin JL, Salic A, Christian KM, Lee LA, Coffey RJ, Lee E. Tahinci E, et al. Among authors: salic a. Development. 2007 Nov;134(22):4095-106. doi: 10.1242/dev.010272. Development. 2007. PMID: 17965054 Free PMC article.
A novel set of Wnt-Frizzled fusion proteins identifies receptor components that activate beta -catenin-dependent signaling.
Holmen SL, Salic A, Zylstra CR, Kirschner MW, Williams BO. Holmen SL, et al. Among authors: salic a. J Biol Chem. 2002 Sep 20;277(38):34727-35. doi: 10.1074/jbc.M204989200. Epub 2002 Jul 16. J Biol Chem. 2002. PMID: 12121999
The roles of APC and Axin derived from experimental and theoretical analysis of the Wnt pathway.
Lee E, Salic A, Krüger R, Heinrich R, Kirschner MW. Lee E, et al. Among authors: salic a. PLoS Biol. 2003 Oct;1(1):E10. doi: 10.1371/journal.pbio.0000010. Epub 2003 Oct 13. PLoS Biol. 2003. PMID: 14551908 Free PMC article.
Processing and turnover of the Hedgehog protein in the endoplasmic reticulum.
Chen X, Tukachinsky H, Huang CH, Jao C, Chu YR, Tang HY, Mueller B, Schulman S, Rapoport TA, Salic A. Chen X, et al. Among authors: salic a. J Cell Biol. 2011 Mar 7;192(5):825-38. doi: 10.1083/jcb.201008090. Epub 2011 Feb 28. J Cell Biol. 2011. PMID: 21357747 Free PMC article.
Cellular Cholesterol Directly Activates Smoothened in Hedgehog Signaling.
Huang P, Nedelcu D, Watanabe M, Jao C, Kim Y, Liu J, Salic A. Huang P, et al. Among authors: salic a. Cell. 2016 Aug 25;166(5):1176-1187.e14. doi: 10.1016/j.cell.2016.08.003. Epub 2016 Aug 18. Cell. 2016. PMID: 27545348 Free PMC article.
Identification of a Paralog-Specific Notch1 Intracellular Domain Degron.
Broadus MR, Chen TW, Neitzel LR, Ng VH, Jodoin JN, Lee LA, Salic A, Robbins DJ, Capobianco AJ, Patton JG, Huppert SS, Lee E. Broadus MR, et al. Among authors: salic a. Cell Rep. 2016 May 31;15(9):1920-9. doi: 10.1016/j.celrep.2016.04.070. Epub 2016 May 19. Cell Rep. 2016. PMID: 27210761 Free PMC article.
Dispatched and scube mediate the efficient secretion of the cholesterol-modified hedgehog ligand.
Tukachinsky H, Kuzmickas RP, Jao CY, Liu J, Salic A. Tukachinsky H, et al. Among authors: salic a. Cell Rep. 2012 Aug 30;2(2):308-20. doi: 10.1016/j.celrep.2012.07.010. Epub 2012 Aug 16. Cell Rep. 2012. PMID: 22902404 Free PMC article.
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