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The following term was not found in PubMed: rygida
Page 1
Showing results for alix rygida
Search for Salix rigida instead (2 results)
Syndecan-syntenin-ALIX regulates the biogenesis of exosomes.
Baietti MF, Zhang Z, Mortier E, Melchior A, Degeest G, Geeraerts A, Ivarsson Y, Depoortere F, Coomans C, Vermeiren E, Zimmermann P, David G. Baietti MF, et al. Nat Cell Biol. 2012 Jun 3;14(7):677-85. doi: 10.1038/ncb2502. Nat Cell Biol. 2012. PMID: 22660413
Here, we report evidence that the syndecan heparan sulphate proteoglycans and their cytoplasmic adaptor syntenin control the formation of exosomes. Syntenin interacts directly with ALIX through LYPX(n)L motifs, similarly to retroviral proteins, and supports the intralumina …
Here, we report evidence that the syndecan heparan sulphate proteoglycans and their cytoplasmic adaptor syntenin control the formation of ex …
ALIX- and ESCRT-III-dependent sorting of tetraspanins to exosomes.
Larios J, Mercier V, Roux A, Gruenberg J. Larios J, et al. J Cell Biol. 2020 Mar 2;219(3):e201904113. doi: 10.1083/jcb.201904113. J Cell Biol. 2020. PMID: 32049272 Free PMC article.
Our data indicate that this ALIX- and ESCRT-III-dependent pathway promotes the sorting and delivery of tetraspanins to exosomes. We conclude that ALIX provides an additional pathway of ILV formation, secondary to the canonical pathway, and that this pathway controls …
Our data indicate that this ALIX- and ESCRT-III-dependent pathway promotes the sorting and delivery of tetraspanins to exosomes. We c …
Galectin-3 Coordinates a Cellular System for Lysosomal Repair and Removal.
Jia J, Claude-Taupin A, Gu Y, Choi SW, Peters R, Bissa B, Mudd MH, Allers L, Pallikkuth S, Lidke KA, Salemi M, Phinney B, Mari M, Reggiori F, Deretic V. Jia J, et al. Dev Cell. 2020 Jan 6;52(1):69-87.e8. doi: 10.1016/j.devcel.2019.10.025. Epub 2019 Dec 5. Dev Cell. 2020. PMID: 31813797 Free PMC article.
Gal3 and its capacity to recognize damage-exposed glycans were required for efficient recruitment of the ESCRT component ALIX during lysosomal damage. Both Gal3 and ALIX were required for restoration of lysosomal function. Gal3 promoted interactions between ALIX …
Gal3 and its capacity to recognize damage-exposed glycans were required for efficient recruitment of the ESCRT component ALIX during …
Targeting the LMP1-ALIX axis in EBV(+) nasopharyngeal carcinoma inhibits immunosuppressive small extracellular vesicle secretion and boosts anti-tumor immunity.
He F, Gong Y, Tao G, Zhang J, Wu Q, Tan Y, Cheng Y, Wang C, Yang J, Han L, Wang Z, Gao Y, He J, Bai R, Sun P, Yu X, Zhou Y, Xie C. He F, et al. Cancer Commun (Lond). 2024 Dec;44(12):1391-1413. doi: 10.1002/cac2.12619. Epub 2024 Oct 14. Cancer Commun (Lond). 2024. PMID: 39402748 Free PMC article.
Mechanistically, LMP1 recruited apoptosis-linked gene 2-interacting protein X (ALIX) through its intracellular domain and bound PD-L1 through its transmembrane domain, thereby facilitating the loading of PD-L1 into ALIX-dependent sEVs. ...CONCLUSION: Our findings un …
Mechanistically, LMP1 recruited apoptosis-linked gene 2-interacting protein X (ALIX) through its intracellular domain and bound PD-L1 …
SUMOylation-triggered ALIX activation modulates extracellular vesicles circTLCD4-RWDD3 to promote lymphatic metastasis of non-small cell lung cancer.
Diao X, Guo C, Zheng H, Zhao K, Luo Y, An M, Lin Y, Chen J, Li Y, Li Y, Gao X, Zhang J, Zhou M, Bai W, Liu L, Wang G, Zhang L, He X, Zhang R, Li Z, Chen C, Li S. Diao X, et al. Signal Transduct Target Ther. 2023 Nov 4;8(1):426. doi: 10.1038/s41392-023-01685-0. Signal Transduct Target Ther. 2023. PMID: 37925421 Free PMC article.
Subsequently, circTLCD4-RWDD3-induced SUMOylated hnRNPA2B1 was recognized by the SUMO interaction motif (SIM) of ALIX and activated ALIX to recruit ESCRT-III, thereby facilitating the sorting of circTLCD4-RWDD3 into NSCLC cell-derived EVs. ...Importantly, blocking E …
Subsequently, circTLCD4-RWDD3-induced SUMOylated hnRNPA2B1 was recognized by the SUMO interaction motif (SIM) of ALIX and activated …
Alix Joffroy (1844-1908).
Teive HAG, Coutinho L, Germiniani FMB, Camargo CHF, Walusinski O. Teive HAG, et al. J Neurol. 2025 Jun 20;272(7):470. doi: 10.1007/s00415-025-13198-7. J Neurol. 2025. PMID: 40540064 No abstract available.
ALIX and TSG101 are essential for cellular entry and replication of two porcine alphacoronaviruses.
Chen X, Liang Y, Weng Z, Hu C, Peng Y, Sun Y, Gao Q, Huang Z, Tang S, Gong L, Zhang G. Chen X, et al. PLoS Pathog. 2024 Mar 15;20(3):e1012103. doi: 10.1371/journal.ppat.1012103. eCollection 2024 Mar. PLoS Pathog. 2024. PMID: 38489378 Free PMC article.
Interestingly, PEAV not only relies on ALIX to regulate viral endocytosis and lysosomal transport, but also requires TSG101 to regulate macropinocytosis. ...PEDV and PEAV replication were significantly inhibited by depletion of ALIX and TSG101 in Vero cells or prima …
Interestingly, PEAV not only relies on ALIX to regulate viral endocytosis and lysosomal transport, but also requires TSG101 to regula …
ALIX and the multivesicular endosome: ALIX in Wonderland.
Bissig C, Gruenberg J. Bissig C, et al. Trends Cell Biol. 2014 Jan;24(1):19-25. doi: 10.1016/j.tcb.2013.10.009. Epub 2013 Nov 26. Trends Cell Biol. 2014. PMID: 24287454 Review.
Despite these differences, recent evidence suggests ALIX and Bro1 share common properties in cargo sorting and ILV formation. We review these commonalities and discuss the role of ALIX in operating 'behind the mirror' during ILV back-fusion with the limiting membran …
Despite these differences, recent evidence suggests ALIX and Bro1 share common properties in cargo sorting and ILV formation. We revi …
Editorial Comment.
Jeffery J, Punjani N. Jeffery J, et al. J Urol. 2025 Aug;214(2):165. doi: 10.1097/JU.0000000000004608. Epub 2025 May 23. J Urol. 2025. PMID: 40407073 No abstract available.
A protocol for exosome isolation and characterization: evaluation of ultracentrifugation, density-gradient separation, and immunoaffinity capture methods.
Greening DW, Xu R, Ji H, Tauro BJ, Simpson RJ. Greening DW, et al. Methods Mol Biol. 2015;1295:179-209. doi: 10.1007/978-1-4939-2550-6_15. Methods Mol Biol. 2015. PMID: 25820723
All exosome isolation methodologies contained 40-150 nm vesicles based on electron microscopy, and positive for exosome markers (Alix, TSG101, HSP70) based on immunoblotting. This protocol employed a proteomic profiling approach to characterize the protein composition of e …
All exosome isolation methodologies contained 40-150 nm vesicles based on electron microscopy, and positive for exosome markers (Alix …
4,568 results