Saltalamacchia A - Search Results

1

Atomic-Level Mechanism of Pre-mRNA Splicing in Health and Disease.

Borišek J, Casalino L, Saltalamacchia A, Mays SG, Malcovati L, Magistrato A. Borišek J, et al. Among authors: saltalamacchia a. Acc Chem Res. 2021 Jan 5;54(1):144-154. doi: 10.1021/acs.accounts.0c00578. Epub 2020 Dec 14. Acc Chem Res. 2021. PMID: 33317262

2

Exploiting Cryo-EM Structural Information and All-Atom Simulations To Decrypt the Molecular Mechanism of Splicing Modulators.

Borišek J, Saltalamacchia A, Spinello A, Magistrato A. Borišek J, et al. Among authors: saltalamacchia a. J Chem Inf Model. 2020 May 26;60(5):2510-2521. doi: 10.1021/acs.jcim.9b00635. Epub 2019 Oct 3. J Chem Inf Model. 2020. PMID: 31539251

3

Disclosing the Impact of Carcinogenic SF3b Mutations on Pre-mRNA Recognition Via All-Atom Simulations.

Borišek J, Saltalamacchia A, Gallì A, Palermo G, Molteni E, Malcovati L, Magistrato A. Borišek J, et al. Among authors: saltalamacchia a. Biomolecules. 2019 Oct 21;9(10):633. doi: 10.3390/biom9100633. Biomolecules. 2019. PMID: 31640290 Free PMC article.

4

Decrypting the Information Exchange Pathways across the Spliceosome Machinery.

Saltalamacchia A, Casalino L, Borišek J, Batista VS, Rivalta I, Magistrato A. Saltalamacchia A, et al. J Am Chem Soc. 2020 May 6;142(18):8403-8411. doi: 10.1021/jacs.0c02036. Epub 2020 Apr 22. J Am Chem Soc. 2020. PMID: 32275149 Free PMC article.

5

Is the Rigidity of SARS-CoV-2 Spike Receptor-Binding Motif the Hallmark for Its Enhanced Infectivity? Insights from All-Atom Simulations.

Spinello A, Saltalamacchia A, Magistrato A. Spinello A, et al. Among authors: saltalamacchia a. J Phys Chem Lett. 2020 Jun 18;11(12):4785-4790. doi: 10.1021/acs.jpclett.0c01148. Epub 2020 Jun 5. J Phys Chem Lett. 2020. PMID: 32463239

6

Allosteric Cross-Talk among Spike's Receptor-Binding Domain Mutations of the SARS-CoV-2 South African Variant Triggers an Effective Hijacking of Human Cell Receptor.

Spinello A, Saltalamacchia A, Borišek J, Magistrato A. Spinello A, et al. Among authors: saltalamacchia a. J Phys Chem Lett. 2021 Jul 1;12(25):5987-5993. doi: 10.1021/acs.jpclett.1c01415. Epub 2021 Jun 23. J Phys Chem Lett. 2021. PMID: 34161095

7

All-Atom Simulations Elucidate the Impact of U2AF2 Cancer-Associated Mutations on Pre-mRNA Recognition.

Rozza R, Saltalamacchia A, Orrico C, Janoš P, Magistrato A. Rozza R, et al. Among authors: saltalamacchia a. J Chem Inf Model. 2022 Dec 26;62(24):6691-6703. doi: 10.1021/acs.jcim.2c00511. Epub 2022 Aug 30. J Chem Inf Model. 2022. PMID: 36040856

8

All-Atom Simulations Disclose How Cytochrome Reductase Reshapes the Substrate Access/Egress Routes of Its Partner CYP450s.

Ritacco I, Saltalamacchia A, Spinello A, Ippoliti E, Magistrato A. Ritacco I, et al. Among authors: saltalamacchia a. J Phys Chem Lett. 2020 Feb 20;11(4):1189-1193. doi: 10.1021/acs.jpclett.9b03798. Epub 2020 Jan 29. J Phys Chem Lett. 2020. PMID: 31986051

9

An oomycete NLP cytolysin forms transient small pores in lipid membranes.

Pirc K, Clifton LA, Yilmaz N, Saltalamacchia A, Mally M, Snoj T, Žnidaršič N, Srnko M, Borišek J, Parkkila P, Albert I, Podobnik M, Numata K, Nürnberger T, Viitala T, Derganc J, Magistrato A, Lakey JH, Anderluh G. Pirc K, et al. Among authors: saltalamacchia a. Sci Adv. 2022 Mar 11;8(10):eabj9406. doi: 10.1126/sciadv.abj9406. Epub 2022 Mar 11. Sci Adv. 2022. PMID: 35275729 Free PMC article.

10

Tracing Allostery in the Spliceosome Ski2-like RNA Helicase Brr2.

Guidarelli Mattioli F, Saltalamacchia A, Magistrato A. Guidarelli Mattioli F, et al. Among authors: saltalamacchia a. J Phys Chem Lett. 2024 Apr 4;15(13):3502-3508. doi: 10.1021/acs.jpclett.3c03538. Epub 2024 Mar 22. J Phys Chem Lett. 2024. PMID: 38517341

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