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Adapting to obesity with adipose tissue inflammation.
Reilly SM, Saltiel AR. Reilly SM, et al. Nat Rev Endocrinol. 2017 Nov;13(11):633-643. doi: 10.1038/nrendo.2017.90. Epub 2017 Aug 11. Nat Rev Endocrinol. 2017. PMID: 28799554 Review.
PPAR gamma and the treatment of insulin resistance.
Olefsky JM, Saltiel AR. Olefsky JM, et al. Trends Endocrinol Metab. 2000 Nov;11(9):362-8. doi: 10.1016/s1043-2760(00)00306-4. Trends Endocrinol Metab. 2000. PMID: 11042466 Review.
Obesity induces a phenotypic switch in adipose tissue macrophage polarization.
Lumeng CN, Bodzin JL, Saltiel AR. Lumeng CN, et al. J Clin Invest. 2007 Jan;117(1):175-84. doi: 10.1172/JCI29881. J Clin Invest. 2007. PMID: 17200717 Free PMC article.
Bone marrow-specific Cap gene deletion protects against high-fat diet-induced insulin resistance.
Lesniewski LA, Hosch SE, Neels JG, de Luca C, Pashmforoush M, Lumeng CN, Chiang SH, Scadeng M, Saltiel AR, Olefsky JM. Lesniewski LA, et al. Nat Med. 2007 Apr;13(4):455-62. doi: 10.1038/nm1550. Epub 2007 Mar 11. Nat Med. 2007. PMID: 17351624
T-ing up inflammation in fat.
Lumeng CN, Maillard I, Saltiel AR. Lumeng CN, et al. Nat Med. 2009 Aug;15(8):846-7. doi: 10.1038/nm0809-846. Nat Med. 2009. PMID: 19661987 No abstract available.
MGL1 promotes adipose tissue inflammation and insulin resistance by regulating 7/4hi monocytes in obesity.
Westcott DJ, Delproposto JB, Geletka LM, Wang T, Singer K, Saltiel AR, Lumeng CN. Westcott DJ, et al. J Exp Med. 2009 Dec 21;206(13):3143-56. doi: 10.1084/jem.20091333. Epub 2009 Dec 7. J Exp Med. 2009. PMID: 19995956 Free PMC article.
Insulin resistance in the defense against obesity.
Saltiel AR. Saltiel AR. Cell Metab. 2012 Jun 6;15(6):798-804. doi: 10.1016/j.cmet.2012.03.001. Cell Metab. 2012. PMID: 22682220
An inhibitor of the protein kinases TBK1 and IKK-ɛ improves obesity-related metabolic dysfunctions in mice.
Reilly SM, Chiang SH, Decker SJ, Chang L, Uhm M, Larsen MJ, Rubin JR, Mowers J, White NM, Hochberg I, Downes M, Yu RT, Liddle C, Evans RM, Oh D, Li P, Olefsky JM, Saltiel AR. Reilly SM, et al. Nat Med. 2013 Mar;19(3):313-21. doi: 10.1038/nm.3082. Epub 2013 Feb 10. Nat Med. 2013. PMID: 23396211 Free PMC article.
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