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A comparative study of sulphonylurea and insulin therapy in non insulin dependent diabetics who had failed on diet therapy alone.
Samanta A, Burden AC, Kinghorn HA. Samanta A, et al. Diabetes Res. 1987 Apr;4(4):183-5. Diabetes Res. 1987. PMID: 3304783 Clinical Trial.
Following a 75 gm OGTT mean plasma insulin at 1/2 hr and 1 hr was 14.0 mu/l and 16.5 mu/l after sulphonylurea, and 23.4 mu/l (p less than 0.05) and 22.1 mu/l (p less than 0.05) after insulin therapy. Plasma C-peptide responses were also improved at 1/2, 1 and 1 1/2 hr afte …
Following a 75 gm OGTT mean plasma insulin at 1/2 hr and 1 hr was 14.0 mu/l and 16.5 mu/l after sulphonylurea, and 23.4 mu/l (p less …
The effect of short term intensive insulin therapy in non-insulin-dependent diabetics who had failed on sulphonylurea therapy.
Samanta A, Burden AC, Jones GR, Clarkson L. Samanta A, et al. Diabetes Res. 1986 Jun;3(5):269-71. Diabetes Res. 1986. PMID: 3527524
All patients were non-ketonuric, had negative islet cell antibodies, and had been on sulphonylureas for a mean duration of 5.6 yr. Patients were maintained at euglycaemia (plasma glucose 4-7 mmol/l) for 24 hr using an open-loop intravenous insulin regimen, and then underwe …
All patients were non-ketonuric, had negative islet cell antibodies, and had been on sulphonylureas for a mean duration of 5.6 yr. Pa …
Insulin secretion to glucose infusion in gestational diabetes subjects with differing DNA polymorphisms flanking the insulin gene.
Samanta A, Burden AC, Jowett NI, Galton DJ, Hosker JP, Turner RC. Samanta A, et al. Diabetes Res. 1987 Mar;4(3):109-12. Diabetes Res. 1987. PMID: 3301158
When not pregnant they were studied by a Constant Glucose Infusion for 1 hr with Model Assessment (CIGMA). The patients with either heterozygous 1/3 alleles or homozygous 1/1 or 3/3 alleles in the 5' flanking region of the insulin gene had similar plasma insulin and C-pept …
When not pregnant they were studied by a Constant Glucose Infusion for 1 hr with Model Assessment (CIGMA). The patients with either h …
Glucose tolerance during pregnancy in Asian women.
Samanta A, Burden ML, Burden AC, Jones GR. Samanta A, et al. Diabetes Res Clin Pract. 1989 Aug 1;7(2):127-35. doi: 10.1016/0168-8227(89)90103-4. Diabetes Res Clin Pract. 1989. PMID: 2776652
The study was divided into two parts: to determine the prevalence of GDM and to determine the level at which glycaemia may impose a risk to the mother and the foetus. Of a total of 12,005 pregnancies (4561 Asian and 7444 White Caucasian), over a 3-year period …
The study was divided into two parts: to determine the prevalence of GDM and to determine the level at which glycaemia may impose a r …
Glucose tolerance following strokes in the elderly.
Samanta A, Blandford RL, Burden AC, Castleden CM. Samanta A, et al. Age Ageing. 1986 Mar;15(2):111-3. doi: 10.1093/ageing/15.2.111. Age Ageing. 1986. PMID: 3962758
Two standard 75 g oral glucose tolerance tests (OGTT) were performed on each of 16 patients, aged 65-84 years, presenting with a thrombotic stroke, and not previously known to have diabetes mellitus. ...Of the remaining ten, there was no worsening of glucose tolerance imme …
Two standard 75 g oral glucose tolerance tests (OGTT) were performed on each of 16 patients, aged 65-84 years, presenting with a thro …
The effects of high dose inhaled beclomethasone dipropionate on glucose and lipid profiles in normal and diet controlled diabetic subjects.
Ebden P, McNally P, Samanta A, Fancourt GJ. Ebden P, et al. Respir Med. 1989 Jul;83(4):289-91. doi: 10.1016/s0954-6111(89)80198-2. Respir Med. 1989. PMID: 2692092 Clinical Trial.
We determined the effect of high doses of inhaled beclomethasone dipropionate (2000 micrograms day-1 for two weeks) on the glucose tolerance test, insulin levels, fasting cholesterol and triglyceride concentrations in fourteen normal and ten elderly diet controlled diabetic patie …
We determined the effect of high doses of inhaled beclomethasone dipropionate (2000 micrograms day-1 for two weeks) on the glucose tolerance …
Insulin and C-peptide in ascitic fluid and plasma and their relative responses to glucagon in patients with cirrhosis.
Akgün S, Samanta A, Ertel NH. Akgün S, et al. J Endocrinol Invest. 1988 Dec;11(11):789-93. doi: 10.1007/BF03350226. J Endocrinol Invest. 1988. PMID: 3066813
After glucagon injection, there was a subnormal rise in plasma glucose (PG) compared to 5 mild diabetic patients without liver disease (8.4 +/- 3.5 vs 76 +/- 7.4 mg/dl). ...After glucagon injection, there was no significant increase in ascitic fluid glucose or IRI, but the …
After glucagon injection, there was a subnormal rise in plasma glucose (PG) compared to 5 mild diabetic patients without liver diseas …
Screening for diabetes in pregnancy: is a random blood glucose enough?
Jowett NI, Samanta AK, Burden AC. Jowett NI, et al. Diabet Med. 1987 Mar-Apr;4(2):160-3. doi: 10.1111/j.1464-5491.1987.tb00854.x. Diabet Med. 1987. PMID: 2952435 Clinical Trial.
It has been suggested that a single random blood glucose measurement, timed in relation to food, can be used to determine those women needing a formal oral glucose tolerance test for the detection of gestational diabetes. ...Random blood glucose measurement is not …
It has been suggested that a single random blood glucose measurement, timed in relation to food, can be used to determine those women …
Effect of peritoneo-venous shunt on portal pressure.
Samanta AK, Leevy CM. Samanta AK, et al. Gut. 1989 Jan;30(1):86-9. doi: 10.1136/gut.30.1.86. Gut. 1989. PMID: 2920931 Free PMC article.
The cause of variceal bleed after a peritoneo-venous shunt is not known. Portal haemodynamic consequences of a peritoneo-venous shunt are poorly understood. ...A sudden increase in portal pressure might be an important provoking factor for variceal bleeding a …
The cause of variceal bleed after a peritoneo-venous shunt is not known. Portal haemodynamic consequences of a peritoneo-venou …
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