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Human electrophysiological correlates of learned irrelevance: effects of the muscarinic M1 antagonist biperiden.
Klinkenberg I, Blokland A, Riedel W, Sambeth A. Klinkenberg I, et al. Int J Neuropsychopharmacol. 2012 Nov;15(10):1375-85. doi: 10.1017/S1461145711001647. Epub 2011 Nov 18. Int J Neuropsychopharmacol. 2012. PMID: 22094124 Free PMC article. Clinical Trial.
Learned irrelevance (LIrr) refers to a reduction in associative learning after pre-exposure of the conditioned and unconditioned stimulus in a non-contingent fashion. This paradigm might serve as a translational model for (pre)attentive information processing …
Learned irrelevance (LIrr) refers to a reduction in associative learning after pre-exposure of the conditioned and unconditioned stim …
Auditory event-related potentials in humans and rats: effects of task manipulation.
Sambeth A, Maes JH, Van Luijtelaar G, Molenkamp IB, Jongsma ML, Van Rijn CM. Sambeth A, et al. Psychophysiology. 2003 Jan;40(1):60-8. doi: 10.1111/1469-8986.00007. Psychophysiology. 2003. PMID: 12751804 Clinical Trial.
Interestingly, effects on the P3 component were similar in the species with regard to amplitude: Target stimuli elicited a higher amplitude in the oddball task than did standard stimuli. ...However, the first four components occurred 1.82 times earlier in rats than in huma …
Interestingly, effects on the P3 component were similar in the species with regard to amplitude: Target stimuli elicited a higher amp …
Enhanced re-habituation of the orienting response of the human event-related potential.
Sambeth A, Maes JH, Quian Quiroga R, Van Rijn CM, Coenen AM. Sambeth A, et al. Neurosci Lett. 2004 Feb 12;356(2):103-6. doi: 10.1016/j.neulet.2003.11.025. Neurosci Lett. 2004. PMID: 14746874
With long intervals, inter-stimulus interval is the critical determinant of the human P300 amplitude.
Sambeth A, Maes JH, Brankack J. Sambeth A, et al. Neurosci Lett. 2004 Apr 15;359(3):143-6. doi: 10.1016/j.neulet.2004.01.064. Neurosci Lett. 2004. PMID: 15050684 Clinical Trial.
The present study tested the validity of this claim at longer intervals in a learning task. Participants were assigned to either an oddball task with an inter-stimulus interval (ISI) of 9-20 s or a single-stimulus task with an ISI of 9-20 or 40-90 s and had to learn …
The present study tested the validity of this claim at longer intervals in a learning task. Participants were assigned to either an o …
Effects of stimulus repetitions on the event-related potential of humans and rats.
Sambeth A, Maes JH, Quian Quiroga R, Coenen AM. Sambeth A, et al. Int J Psychophysiol. 2004 Aug;53(3):197-205. doi: 10.1016/j.ijpsycho.2004.04.004. Int J Psychophysiol. 2004. PMID: 15246673 Clinical Trial.
Both species were presented with a total of 100 auditory stimuli, divided into four blocks of 25 stimuli. By means of wavelet denoising, single-trial ERPs were established in both humans and rats. ...In both humans and rats, response decrements within a block were t …
Both species were presented with a total of 100 auditory stimuli, divided into four blocks of 25 stimuli. By means of wavelet denoisi …
Sex differences in the effect of acute tryptophan depletion on declarative episodic memory: a pooled analysis of nine studies.
Sambeth A, Blokland A, Harmer CJ, Kilkens TO, Nathan PJ, Porter RJ, Schmitt JA, Scholtissen B, Sobczak S, Young AH, Riedel WJ. Sambeth A, et al. Neurosci Biobehav Rev. 2007;31(4):516-29. doi: 10.1016/j.neubiorev.2006.11.009. Epub 2007 Jan 16. Neurosci Biobehav Rev. 2007. PMID: 17229463 Review.
Acute tryptophan depletion (ATD) studies have shown that serotonin plays a role in learning and memory processes. In this study, we performed a pooled analysis of nine ATD studies in order to examine the nature of the memory-impairing effects of ATD and mediating fa …
Acute tryptophan depletion (ATD) studies have shown that serotonin plays a role in learning and memory processes. In this study, we p …
Cholinergic drugs affect novel object recognition in rats: relation with hippocampal EEG?
Sambeth A, Riedel WJ, Smits LT, Blokland A. Sambeth A, et al. Eur J Pharmacol. 2007 Oct 31;572(2-3):151-9. doi: 10.1016/j.ejphar.2007.06.018. Epub 2007 Jun 27. Eur J Pharmacol. 2007. PMID: 17659275
It is suggested that scopolamine caused a decrement in arousal in this study. Furthermore, the current results suggest a relation between EEG and object memory after cholinergic drug treatment. However, there was a clear dissociation between memory performanc …
It is suggested that scopolamine caused a decrement in arousal in this study. Furthermore, the current results suggest a relat …
Somatosensory evoked magnetic fields from the primary and secondary somatosensory cortices in healthy newborns.
Nevalainen P, Lauronen L, Sambeth A, Wikström H, Okada Y, Pihko E. Nevalainen P, et al. Neuroimage. 2008 Apr 1;40(2):738-745. doi: 10.1016/j.neuroimage.2007.09.075. Epub 2007 Dec 27. Neuroimage. 2008. PMID: 18234514
Activity in this area was strongly depressed by a faster rate of stimulation. Ipsilateral activity was seen in most subjects: more often in QS than AS. ...
Activity in this area was strongly depressed by a faster rate of stimulation. Ipsilateral activity was seen in most subjects: more of …
Memory impairments in humans after acute tryptophan depletion using a novel gelatin-based protein drink.
Sambeth A, Riedel WJ, Tillie DE, Blokland A, Postma A, Schmitt JA. Sambeth A, et al. J Psychopharmacol. 2009 Jan;23(1):56-64. doi: 10.1177/0269881108089577. Epub 2008 May 30. J Psychopharmacol. 2009. PMID: 18515454 Clinical Trial.
This study used a recently developed gelatin-based protein drink to examine whether it 1) is superior to the traditional AA method in controlling the tryptophan levels in the placebo condition, 2) impairs long-term memory and 3) differentially affects episodic and spatial …
This study used a recently developed gelatin-based protein drink to examine whether it 1) is superior to the traditional AA method in …
Change detection in newborns using a multiple deviant paradigm: a study using magnetoencephalography.
Sambeth A, Pakarinen S, Ruohio K, Fellman V, van Zuijen TL, Huotilainen M. Sambeth A, et al. Clin Neurophysiol. 2009 Mar;120(3):530-8. doi: 10.1016/j.clinph.2008.12.033. Epub 2009 Feb 10. Clin Neurophysiol. 2009. PMID: 19211303
We employed a multiple deviant paradigm for a fast assessment of the ability of the newborn brain to respond to various types of acoustic changes. ...Between repeated stimuli, four types of acoustic changes (frequency, intensity, duration, and a gap) were pre …
We employed a multiple deviant paradigm for a fast assessment of the ability of the newborn brain to respond to various types …
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