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LAT is required for TCR-mediated activation of PLCgamma1 and the Ras pathway.
Finco TS, Kadlecek T, Zhang W, Samelson LE, Weiss A. Finco TS, et al. Among authors: samelson le. Immunity. 1998 Nov;9(5):617-26. doi: 10.1016/s1074-7613(00)80659-7. Immunity. 1998. PMID: 9846483
Cutting edge: a role for the adaptor protein LAT in human NK cell-mediated cytotoxicity.
Jevremovic D, Billadeau DD, Schoon RA, Dick CJ, Irvin BJ, Zhang W, Samelson LE, Abraham RT, Leibson PJ. Jevremovic D, et al. Among authors: samelson le. J Immunol. 1999 Mar 1;162(5):2453-6. J Immunol. 1999. PMID: 10072481
LAT is required for tyrosine phosphorylation of phospholipase cgamma2 and platelet activation by the collagen receptor GPVI.
Pasquet JM, Gross B, Quek L, Asazuma N, Zhang W, Sommers CL, Schweighoffer E, Tybulewicz V, Judd B, Lee JR, Koretzky G, Love PE, Samelson LE, Watson SP. Pasquet JM, et al. Among authors: samelson le. Mol Cell Biol. 1999 Dec;19(12):8326-34. doi: 10.1128/mcb.19.12.8326. Mol Cell Biol. 1999. PMID: 10567557 Free PMC article.
The role of membrane-associated adaptors in T cell receptor signalling.
Zhang W, Samelson LE. Zhang W, et al. Among authors: samelson le. Semin Immunol. 2000 Feb;12(1):35-41. doi: 10.1006/smim.2000.0205. Semin Immunol. 2000. PMID: 10723796 Review.
Enhanced T-cell activation and differentiation in lymphocytes from transgenic mice expressing ubiquitination-resistant 2KR LAT molecules.
Rodriguez-Peña AB, Gomez-Rodriguez J, Kortum RL, Palmer DC, Yu Z, Guittard GC, Wohlfert EA, Silver PB, Misplon JA, Sommers CL, Feigenbaum L, Epstein SL, Caspi RR, Belkaid Y, Restifo NP, Samelson LE, Balagopalan L. Rodriguez-Peña AB, et al. Among authors: samelson le. Gene Ther. 2015 Oct;22(10):781-92. doi: 10.1038/gt.2015.48. Epub 2015 Jun 18. Gene Ther. 2015. PMID: 26018935 Free PMC article.
Key molecules involved in receptor-mediated lymphocyte activation.
O'Shea JJ, Johnston JA, Kehrl J, Koretzky G, Samelson LE. O'Shea JJ, et al. Among authors: samelson le. Curr Protoc Immunol. 2001 Nov;Chapter 11:Unit 11.9A. doi: 10.1002/0471142735.im1109as44. Curr Protoc Immunol. 2001. PMID: 18432708 Review.
Studies on the adapter molecule LAT.
Samelson LE, Bunnell SC, Trible RP, Yamazaki T, Zhang W. Samelson LE, et al. Cold Spring Harb Symp Quant Biol. 1999;64:259-63. doi: 10.1101/sqb.1999.64.259. Cold Spring Harb Symp Quant Biol. 1999. PMID: 11232294 Review. No abstract available.
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