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Enhanced T-cell activation and differentiation in lymphocytes from transgenic mice expressing ubiquitination-resistant 2KR LAT molecules.
Rodriguez-Peña AB, Gomez-Rodriguez J, Kortum RL, Palmer DC, Yu Z, Guittard GC, Wohlfert EA, Silver PB, Misplon JA, Sommers CL, Feigenbaum L, Epstein SL, Caspi RR, Belkaid Y, Restifo NP, Samelson LE, Balagopalan L. Rodriguez-Peña AB, et al. Among authors: samelson le. Gene Ther. 2015 Oct;22(10):781-92. doi: 10.1038/gt.2015.48. Epub 2015 Jun 18. Gene Ther. 2015. PMID: 26018935 Free PMC article.
Key molecules involved in receptor-mediated lymphocyte activation.
O'Shea JJ, Johnston JA, Kehrl J, Koretzky G, Samelson LE. O'Shea JJ, et al. Among authors: samelson le. Curr Protoc Immunol. 2001 Nov;Chapter 11:Unit 11.9A. doi: 10.1002/0471142735.im1109as44. Curr Protoc Immunol. 2001. PMID: 18432708 Review.
LAT is essential for Fc(epsilon)RI-mediated mast cell activation.
Saitoh S, Arudchandran R, Manetz TS, Zhang W, Sommers CL, Love PE, Rivera J, Samelson LE. Saitoh S, et al. Among authors: samelson le. Immunity. 2000 May;12(5):525-35. doi: 10.1016/s1074-7613(00)80204-6. Immunity. 2000. PMID: 10843385
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