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The sorting protein PACS-2 promotes ErbB signalling by regulating recycling of the metalloproteinase ADAM17.
Dombernowsky SL, Samsøe-Petersen J, Petersen CH, Instrell R, Hedegaard AM, Thomas L, Atkins KM, Auclair S, Albrechtsen R, Mygind KJ, Fröhlich C, Howell M, Parker P, Thomas G, Kveiborg M. Dombernowsky SL, et al. Among authors: samsoe petersen j. Nat Commun. 2015 Jun 25;6:7518. doi: 10.1038/ncomms8518. Nat Commun. 2015. PMID: 26108729 Free PMC article.
Mechanisms of site-specific dephosphorylation and kinase opposition imposed by PP2A regulatory subunits.
Kruse T, Gnosa SP, Nasa I, Garvanska DH, Hein JB, Nguyen H, Samsøe-Petersen J, Lopez-Mendez B, Hertz EPT, Schwarz J, Pena HS, Nikodemus D, Kveiborg M, Kettenbach AN, Nilsson J. Kruse T, et al. Among authors: samsoe petersen j. EMBO J. 2020 Jul 1;39(13):e103695. doi: 10.15252/embj.2019103695. Epub 2020 May 13. EMBO J. 2020. PMID: 32400009 Free PMC article.
ADAM12 expression is upregulated in cancer cells upon radiation and constitutes a prognostic factor in rectal cancer patients following radiotherapy.
Piotrowski KB, Blasco LP, Samsøe-Petersen J, Eefsen RL, Illemann M, Oria VO, Campos KIA, Lopresti AM, Albrechtsen R, Sørensen CS, Sun XF, Kveiborg M, Gnosa S. Piotrowski KB, et al. Among authors: samsoe petersen j. Cancer Gene Ther. 2023 Oct;30(10):1369-1381. doi: 10.1038/s41417-023-00643-w. Epub 2023 Jul 26. Cancer Gene Ther. 2023. PMID: 37495855 Free PMC article.