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Protein folding drives disulfide formation.
Kosuri P, Alegre-Cebollada J, Feng J, Kaplan A, Inglés-Prieto A, Badilla CL, Stockwell BR, Sanchez-Ruiz JM, Holmgren A, Fernández JM. Kosuri P, et al. Cell. 2012 Nov 9;151(4):794-806. doi: 10.1016/j.cell.2012.09.036. Cell. 2012. PMID: 23141538 Free PMC article.
Probing the chemistry of thioredoxin catalysis with force.
Wiita AP, Perez-Jimenez R, Walther KA, Gräter F, Berne BJ, Holmgren A, Sanchez-Ruiz JM, Fernandez JM. Wiita AP, et al. Nature. 2007 Nov 1;450(7166):124-7. doi: 10.1038/nature06231. Nature. 2007. PMID: 17972886 Free PMC article.
Force-clamp spectroscopy detects residue co-evolution in enzyme catalysis.
Perez-Jimenez R, Wiita AP, Rodriguez-Larrea D, Kosuri P, Gavira JA, Sanchez-Ruiz JM, Fernandez JM. Perez-Jimenez R, et al. J Biol Chem. 2008 Oct 3;283(40):27121-9. doi: 10.1074/jbc.M803746200. Epub 2008 Aug 7. J Biol Chem. 2008. PMID: 18687682 Free PMC article.
Diversity of chemical mechanisms in thioredoxin catalysis revealed by single-molecule force spectroscopy.
Perez-Jimenez R, Li J, Kosuri P, Sanchez-Romero I, Wiita AP, Rodriguez-Larrea D, Chueca A, Holmgren A, Miranda-Vizuete A, Becker K, Cho SH, Beckwith J, Gelhaye E, Jacquot JP, Gaucher EA, Sanchez-Ruiz JM, Berne BJ, Fernandez JM. Perez-Jimenez R, et al. Nat Struct Mol Biol. 2009 Aug;16(8):890-6. doi: 10.1038/nsmb.1627. Epub 2009 Jul 13. Nat Struct Mol Biol. 2009. PMID: 19597482 Free PMC article.
Role of conservative mutations in protein multi-property adaptation.
Rodriguez-Larrea D, Perez-Jimenez R, Sanchez-Romero I, Delgado-Delgado A, Fernandez JM, Sanchez-Ruiz JM. Rodriguez-Larrea D, et al. Biochem J. 2010 Jul 15;429(2):243-9. doi: 10.1042/BJ20100386. Biochem J. 2010. PMID: 20446918 Free PMC article.
Single-molecule paleoenzymology probes the chemistry of resurrected enzymes.
Perez-Jimenez R, Inglés-Prieto A, Zhao ZM, Sanchez-Romero I, Alegre-Cebollada J, Kosuri P, Garcia-Manyes S, Kappock TJ, Tanokura M, Holmgren A, Sanchez-Ruiz JM, Gaucher EA, Fernandez JM. Perez-Jimenez R, et al. Nat Struct Mol Biol. 2011 May;18(5):592-6. doi: 10.1038/nsmb.2020. Epub 2011 Apr 3. Nat Struct Mol Biol. 2011. PMID: 21460845 Free PMC article.
Conservation of protein structure over four billion years.
Ingles-Prieto A, Ibarra-Molero B, Delgado-Delgado A, Perez-Jimenez R, Fernandez JM, Gaucher EA, Sanchez-Ruiz JM, Gavira JA. Ingles-Prieto A, et al. Structure. 2013 Sep 3;21(9):1690-7. doi: 10.1016/j.str.2013.06.020. Epub 2013 Aug 8. Structure. 2013. PMID: 23932589 Free PMC article.
126 results