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Principles of lysosomal membrane digestion: stimulation of sphingolipid degradation by sphingolipid activator proteins and anionic lysosomal lipids.
Kolter T, Sandhoff K. Kolter T, et al. Among authors: sandhoff k. Annu Rev Cell Dev Biol. 2005;21:81-103. doi: 10.1146/annurev.cellbio.21.122303.120013. Annu Rev Cell Dev Biol. 2005. PMID: 16212488 Review.
Molecular analysis of acid ceramidase deficiency in patients with Farber disease.
Bär J, Linke T, Ferlinz K, Neumann U, Schuchman EH, Sandhoff K. Bär J, et al. Among authors: sandhoff k. Hum Mutat. 2001 Mar;17(3):199-209. doi: 10.1002/humu.5. Hum Mutat. 2001. PMID: 11241842
Physiology and pathophysiology of sphingolipid metabolism and signaling.
Huwiler A, Kolter T, Pfeilschifter J, Sandhoff K. Huwiler A, et al. Among authors: sandhoff k. Biochim Biophys Acta. 2000 May 31;1485(2-3):63-99. doi: 10.1016/s1388-1981(00)00042-1. Biochim Biophys Acta. 2000. PMID: 10832090 Review. No abstract available.
Quantification of mRNAs encoding proteins of the glycosphingolipid catabolism in mouse models of GM2 gangliosidoses and sphingolipid activator protein precursor (prosaposin) deficiency.
Potratz A, Hüttler S, Bierfreund U, Proia RL, Suzuki K, Sandhoff K. Potratz A, et al. Among authors: sandhoff k. Biochim Biophys Acta. 2000 Nov 15;1502(3):391-7. doi: 10.1016/s0925-4439(00)00063-6. Biochim Biophys Acta. 2000. PMID: 11068181
Glycosphingolipid specificity of the human sulfatide activator protein.
Vogel A, Schwarzmann G, Sandhoff K. Vogel A, et al. Among authors: sandhoff k. Eur J Biochem. 1991 Sep 1;200(2):591-7. doi: 10.1111/j.1432-1033.1991.tb16222.x. Eur J Biochem. 1991. PMID: 1889421
Analysis of a splice-site mutation in the sap-precursor gene of a patient with metachromatic leukodystrophy.
Henseler M, Klein A, Reber M, Vanier MT, Landrieu P, Sandhoff K. Henseler M, et al. Among authors: sandhoff k. Am J Hum Genet. 1996 Jan;58(1):65-74. Am J Hum Genet. 1996. PMID: 8554069 Free PMC article.
The urine from patients with peritonitis as a rich source for purifying human acid sphingomyelinase and other lysosomal enzymes.
Quintern LE, Zenk TS, Sandhoff K. Quintern LE, et al. Among authors: sandhoff k. Biochim Biophys Acta. 1989 Jun 8;1003(2):121-4. doi: 10.1016/0005-2760(89)90244-0. Biochim Biophys Acta. 1989. PMID: 2543449
Topology of glycosphingolipid degradation.
Sandhoff K, Kolter T. Sandhoff K, et al. Trends Cell Biol. 1996 Mar;6(3):98-103. doi: 10.1016/0962-8924(96)80999-8. Trends Cell Biol. 1996. PMID: 15157485
Accumulation of sphingolipids in SAP-precursor (prosaposin)-deficient fibroblasts occurs as intralysosomal membrane structures and can be completely reversed by treatment with human SAP-precursor.
Burkhardt JK, Hüttler S, Klein A, Möbius W, Habermann A, Griffiths G, Sandhoff K. Burkhardt JK, et al. Among authors: sandhoff k. Eur J Cell Biol. 1997 May;73(1):10-8. Eur J Cell Biol. 1997. PMID: 9174667
The results support our hypothesis that endocytosis of plasma membrane-derived lipids occurs via small intraendosomal and intralysosomal vesicles and membrane structures that are then digested within the lysosomes (Sandhoff, K., T. Kolter, Trends in Cell Biol. 6, 98 …
The results support our hypothesis that endocytosis of plasma membrane-derived lipids occurs via small intraendosomal and intralysosomal ves …
Sphingolipid activator proteins: proteins with complex functions in lipid degradation and skin biogenesis.
Schuette CG, Pierstorff B, Huettler S, Sandhoff K. Schuette CG, et al. Among authors: sandhoff k. Glycobiology. 2001 Jun;11(6):81R-90R. doi: 10.1093/glycob/11.6.81r. Glycobiology. 2001. PMID: 11445546 Review.
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