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Genetic susceptibility to type 2 diabetes and obesity: from genome-wide association studies to rare variants and beyond.
Grarup N, Sandholt CH, Hansen T, Pedersen O. Grarup N, et al. Among authors: sandholt ch. Diabetologia. 2014 Aug;57(8):1528-41. doi: 10.1007/s00125-014-3270-4. Epub 2014 May 24. Diabetologia. 2014. PMID: 24859358 Review.
Combined analyses of 20 common obesity susceptibility variants.
Sandholt CH, Sparsø T, Grarup N, Albrechtsen A, Almind K, Hansen L, Toft U, Jørgensen T, Hansen T, Pedersen O. Sandholt CH, et al. Diabetes. 2010 Jul;59(7):1667-73. doi: 10.2337/db09-1042. Epub 2010 Jan 28. Diabetes. 2010. PMID: 20110568 Free PMC article. Clinical Trial.
Studies of association between LPIN1 variants and common metabolic phenotypes among 17,538 Danes.
Burgdorf KS, Sandholt CH, Sparsø T, Andersen G, Witte DR, Jørgensen T, Sandbaek A, Lauritzen T, Sørensen TI, Madsbad S, Hansen T, Pedersen O. Burgdorf KS, et al. Among authors: sandholt ch. Eur J Endocrinol. 2010 Jul;163(1):81-7. doi: 10.1530/EJE-10-0068. Epub 2010 Mar 31. Eur J Endocrinol. 2010. PMID: 20356931
Do gene variants influencing adult adiposity affect birth weight? A population-based study of 24 loci in 4,744 Danish individuals.
Andersson EA, Pilgaard K, Pisinger C, Harder MN, Grarup N, Færch K, Sandholt C, Poulsen P, Witte DR, Jørgensen T, Vaag A, Pedersen O, Hansen T. Andersson EA, et al. PLoS One. 2010 Dec 1;5(12):e14190. doi: 10.1371/journal.pone.0014190. PLoS One. 2010. PMID: 21152014 Free PMC article.
The minor C-allele of rs2014355 in ACADS is associated with reduced insulin release following an oral glucose load.
Hornbak M, Banasik K, Justesen JM, Krarup NT, Sandholt CH, Andersson Å, Sandbæk A, Lauritzen T, Pisinger C, Witte DR, Sørensen TA, Pedersen O, Hansen T. Hornbak M, et al. Among authors: sandholt ch. BMC Med Genet. 2011 Jan 6;12:4. doi: 10.1186/1471-2350-12-4. BMC Med Genet. 2011. PMID: 21211036 Free PMC article.
Bioinformatics-driven identification and examination of candidate genes for non-alcoholic fatty liver disease.
Banasik K, Justesen JM, Hornbak M, Krarup NT, Gjesing AP, Sandholt CH, Jensen TS, Grarup N, Andersson A, Jørgensen T, Witte DR, Sandbæk A, Lauritzen T, Thorens B, Brunak S, Sørensen TI, Pedersen O, Hansen T. Banasik K, et al. Among authors: sandholt ch. PLoS One. 2011 Jan 27;6(1):e16542. doi: 10.1371/journal.pone.0016542. PLoS One. 2011. PMID: 21339799 Free PMC article.
Implications of central obesity-related variants in LYPLAL1, NRXN3, MSRA, and TFAP2B on quantitative metabolic traits in adult Danes.
Bille DS, Banasik K, Justesen JM, Sandholt CH, Sandbæk A, Lauritzen T, Jørgensen T, Witte DR, Holm JC, Hansen T, Pedersen O. Bille DS, et al. Among authors: sandholt ch. PLoS One. 2011;6(6):e20640. doi: 10.1371/journal.pone.0020640. Epub 2011 Jun 2. PLoS One. 2011. PMID: 21674055 Free PMC article.
Studies of metabolic phenotypic correlates of 15 obesity associated gene variants.
Sandholt CH, Vestmar MA, Bille DS, Borglykke A, Almind K, Hansen L, Sandbæk A, Lauritzen T, Witte D, Jørgensen T, Pedersen O, Hansen T. Sandholt CH, et al. PLoS One. 2011;6(9):e23531. doi: 10.1371/journal.pone.0023531. Epub 2011 Sep 2. PLoS One. 2011. PMID: 21912638 Free PMC article.
Association studies of novel obesity-related gene variants with quantitative metabolic phenotypes in a population-based sample of 6,039 Danish individuals.
Burgdorf KS, Gjesing AP, Grarup N, Justesen JM, Sandholt CH, Witte DR, Jørgensen T, Madsbad S, Hansen T, Pedersen O. Burgdorf KS, et al. Among authors: sandholt ch. Diabetologia. 2012 Jan;55(1):105-13. doi: 10.1007/s00125-011-2320-4. Epub 2011 Sep 28. Diabetologia. 2012. PMID: 21953277 Clinical Trial.
Physical activity attenuates the influence of FTO variants on obesity risk: a meta-analysis of 218,166 adults and 19,268 children.
Kilpeläinen TO, Qi L, Brage S, Sharp SJ, Sonestedt E, Demerath E, Ahmad T, Mora S, Kaakinen M, Sandholt CH, Holzapfel C, Autenrieth CS, Hyppönen E, Cauchi S, He M, Kutalik Z, Kumari M, Stančáková A, Meidtner K, Balkau B, Tan JT, Mangino M, Timpson NJ, Song Y, Zillikens MC, Jablonski KA, Garcia ME, Johansson S, Bragg-Gresham JL, Wu Y, van Vliet-Ostaptchouk JV, Onland-Moret NC, Zimmermann E, Rivera NV, Tanaka T, Stringham HM, Silbernagel G, Kanoni S, Feitosa MF, Snitker S, Ruiz JR, Metter J, Larrad MT, Atalay M, Hakanen M, Amin N, Cavalcanti-Proença C, Grøntved A, Hallmans G, Jansson JO, Kuusisto J, Kähönen M, Lutsey PL, Nolan JJ, Palla L, Pedersen O, Pérusse L, Renström F, Scott RA, Shungin D, Sovio U, Tammelin TH, Rönnemaa T, Lakka TA, Uusitupa M, Rios MS, Ferrucci L, Bouchard C, Meirhaeghe A, Fu M, Walker M, Borecki IB, Dedoussis GV, Fritsche A, Ohlsson C, Boehnke M, Bandinelli S, van Duijn CM, Ebrahim S, Lawlor DA, Gudnason V, Harris TB, Sørensen TI, Mohlke KL, Hofman A, Uitterlinden AG, Tuomilehto J, Lehtimäki T, Raitakari O, Isomaa B, Njølstad PR, Florez JC, Liu S, Ness A, Spector TD, Tai ES, Froguel P, Boeing H, Laakso M, Marmot M, Bergmann S, Power C, Khaw KT, Chasman D, Ridker P, Hansen T, Monda KL, Illig T, Järvelin MR, Wareham NJ, Hu FB, Groop LC, Orho-Melander M, Ekelund U, Franks PW, Loos RJ. Kilpeläinen TO, et al. Among authors: sandholt ch. PLoS Med. 2011 Nov;8(11):e1001116. doi: 10.1371/journal.pmed.1001116. Epub 2011 Nov 1. PLoS Med. 2011. PMID: 22069379 Free PMC article.
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