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Enhanced Cardiomyocyte Function in Hypertensive Rats With Diastolic Dysfunction and Human Heart Failure Patients After Acute Treatment With Soluble Guanylyl Cyclase (sGC) Activator.
Kolijn D, Kovács Á, Herwig M, Lódi M, Sieme M, Alhaj A, Sandner P, Papp Z, Reusch PH, Haldenwang P, Falcão-Pires I, Linke WA, Jaquet K, Van Linthout S, Mügge A, Tschöpe C, Hamdani N. Kolijn D, et al. Among authors: sandner p. Front Physiol. 2020 May 25;11:345. doi: 10.3389/fphys.2020.00345. eCollection 2020. Front Physiol. 2020. PMID: 32523538 Free PMC article.
Testosterone Induces Relaxation of Human Corpus Cavernosum Tissue of Patients With Erectile Dysfunction.
Van den Broeck T, Soebadi MA, Falter A, Raets L, Duponselle J, Lootsma J, Heintz A, Philtjens U, Hofkens L, Gonzalez-Viedma A, Driesen K, Sandner P, Albersen M, Brône B, Van Renterghem K. Van den Broeck T, et al. Among authors: sandner p. Sex Med. 2020 Mar;8(1):114-119. doi: 10.1016/j.esxm.2019.10.003. Epub 2019 Nov 22. Sex Med. 2020. PMID: 31767508 Free PMC article.
Beneficial Effects of Soluble Guanylyl Cyclase Stimulation and Activation in Sickle Cell Disease Are Amplified by Hydroxyurea: In Vitro and In Vivo Studies.
Ferreira WA Jr, Chweih H, Lanaro C, Almeida CB, Brito PL, Gotardo EMF, Torres L, Miguel LI, Franco-Penteado CF, Leonardo FC, Garcia F, Saad STO, Frenette PS, Brockschnieder D, Costa FF, Stasch JP, Sandner P, Conran N. Ferreira WA Jr, et al. Among authors: sandner p. J Pharmacol Exp Ther. 2020 Sep;374(3):469-478. doi: 10.1124/jpet.119.264606. Epub 2020 Jul 6. J Pharmacol Exp Ther. 2020. PMID: 32631869 Free PMC article.
Discovery of the Soluble Guanylate Cyclase Activator Runcaciguat (BAY 1101042).
Hahn MG, Lampe T, El Sheikh S, Griebenow N, Woltering E, Schlemmer KH, Dietz L, Gerisch M, Wunder F, Becker-Pelster EM, Mondritzki T, Tinel H, Knorr A, Kern A, Lang D, Hueser J, Schomber T, Benardeau A, Eitner F, Truebel H, Mittendorf J, Kumar V, van den Akker F, Schaefer M, Geiss V, Sandner P, Stasch JP. Hahn MG, et al. Among authors: sandner p. J Med Chem. 2021 Apr 19. doi: 10.1021/acs.jmedchem.0c02154. Online ahead of print. J Med Chem. 2021. PMID: 33872507
Mineralocorticoid receptor antagonism by finerenone is sufficient to improve function in preclinical muscular dystrophy.
Lowe J, Kolkhof P, Haupt MJ, Peczkowski KK, Rastogi N, Hauck JS, Kadakia FK, Zins JG, Ciccone PC, Smart S, Sandner P, Raman SV, Janssen PML, Rafael-Fortney JA. Lowe J, et al. Among authors: sandner p. ESC Heart Fail. 2020 Sep 18;7(6):3983-95. doi: 10.1002/ehf2.12996. Online ahead of print. ESC Heart Fail. 2020. PMID: 32945624 Free PMC article.
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