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BRL37344 stimulates GLUT4 translocation and glucose uptake in skeletal muscle via β2-adrenoceptors without causing classical receptor desensitization.
Mukaida S, Sato M, Öberg AI, Dehvari N, Olsen JM, Kocan M, Halls ML, Merlin J, Sandström AL, Csikasz RI, Evans BA, Summers RJ, Hutchinson DS, Bengtsson T. Mukaida S, et al. Among authors: sandstrom al. Am J Physiol Regul Integr Comp Physiol. 2019 May 1;316(5):R666-R677. doi: 10.1152/ajpregu.00285.2018. Epub 2019 Mar 20. Am J Physiol Regul Integr Comp Physiol. 2019. PMID: 30892909 Free article.
Treatment with a β-2-adrenoceptor agonist stimulates glucose uptake in skeletal muscle and improves glucose homeostasis, insulin resistance and hepatic steatosis in mice with diet-induced obesity.
Kalinovich A, Dehvari N, Åslund A, van Beek S, Halleskog C, Olsen J, Forsberg E, Zacharewicz E, Schaart G, Rinde M, Sandström A, Berlin R, Östenson CG, Hoeks J, Bengtsson T. Kalinovich A, et al. Diabetologia. 2020 Aug;63(8):1603-1615. doi: 10.1007/s00125-020-05171-y. Epub 2020 May 29. Diabetologia. 2020. PMID: 32472192 Free PMC article.
α1A-Adrenoceptors activate mTOR signalling and glucose uptake in cardiomyocytes.
Sato M, Evans BA, Sandström AL, Chia LY, Mukaida S, Thai BS, Nguyen A, Lim L, Tan CYR, Baltos JA, White PJ, May LT, Hutchinson DS, Summers RJ, Bengtsson T. Sato M, et al. Among authors: sandstrom al. Biochem Pharmacol. 2018 Feb;148:27-40. doi: 10.1016/j.bcp.2017.11.016. Epub 2017 Nov 24. Biochem Pharmacol. 2018. PMID: 29175420 Free article.
Most youth with type 1 diabetes in the T1D Exchange Clinic Registry do not meet American Diabetes Association or International Society for Pediatric and Adolescent Diabetes clinical guidelines.
Wood JR, Miller KM, Maahs DM, Beck RW, DiMeglio LA, Libman IM, Quinn M, Tamborlane WV, Woerner SE; T1D Exchange Clinic Network. Wood JR, et al. Diabetes Care. 2013 Jul;36(7):2035-7. doi: 10.2337/dc12-1959. Epub 2013 Jan 22. Diabetes Care. 2013. PMID: 23340893 Free PMC article.
Longitudinal Changes in Continuous Glucose Monitoring Use Among Individuals With Type 1 Diabetes: International Comparison in the German and Austrian DPV and U.S. T1D Exchange Registries.
Miller KM, Hermann J, Foster N, Hofer SE, Rickels MR, Danne T, Clements MA, Lilienthal E, Maahs DM, Holl RW; T1D Exchange and DPV Registries. Miller KM, et al. Diabetes Care. 2020 Jan;43(1):e1-e2. doi: 10.2337/dc19-1214. Epub 2019 Oct 31. Diabetes Care. 2020. PMID: 31672703 Free PMC article. No abstract available.
13 results