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Hijacking HES1: how tumors co-opt the anti-differentiation strategies of quiescent cells.

Sang L, Roberts JM, Coller HA. Sang L, et al. Trends Mol Med. 2010 Jan;16(1):17-26. doi: 10.1016/j.molmed.2009.11.001. Epub 2009 Dec 18. Trends Mol Med. 2010. PMID: 20022559 Free PMC article. Review.

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Fear of commitment: Hes1 protects quiescent fibroblasts from irreversible cellular fates.

Sang L, Coller HA. Sang L, et al. Cell Cycle. 2009 Jul 15;8(14):2161-7. doi: 10.4161/cc.8.14.9104. Epub 2009 Jul 26. Cell Cycle. 2009. PMID: 19587546

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Control of the reversibility of cellular quiescence by the transcriptional repressor HES1.

Sang L, Coller HA, Roberts JM. Sang L, et al. Science. 2008 Aug 22;321(5892):1095-100. doi: 10.1126/science.1155998. Science. 2008. PMID: 18719287 Free PMC article.

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An ARL3-UNC119-RP2 GTPase cycle targets myristoylated NPHP3 to the primary cilium.

Wright KJ, Baye LM, Olivier-Mason A, Mukhopadhyay S, Sang L, Kwong M, Wang W, Pretorius PR, Sheffield VC, Sengupta P, Slusarski DC, Jackson PK. Wright KJ, et al. Among authors: sang l. Genes Dev. 2011 Nov 15;25(22):2347-60. doi: 10.1101/gad.173443.111. Genes Dev. 2011. PMID: 22085962 Free PMC article.

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A new description of cellular quiescence.

Coller HA, Sang L, Roberts JM. Coller HA, et al. Among authors: sang l. PLoS Biol. 2006 Mar;4(3):e83. doi: 10.1371/journal.pbio.0040083. Epub 2006 Mar 7. PLoS Biol. 2006. PMID: 16509772 Free PMC article.

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Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways.

Sang L, Miller JJ, Corbit KC, Giles RH, Brauer MJ, Otto EA, Baye LM, Wen X, Scales SJ, Kwong M, Huntzicker EG, Sfakianos MK, Sandoval W, Bazan JF, Kulkarni P, Garcia-Gonzalo FR, Seol AD, O'Toole JF, Held S, Reutter HM, Lane WS, Rafiq MA, Noor A, Ansar M, Devi AR, Sheffield VC, Slusarski DC, Vincent JB, Doherty DA, Hildebrandt F, Reiter JF, Jackson PK. Sang L, et al. Cell. 2011 May 13;145(4):513-28. doi: 10.1016/j.cell.2011.04.019. Cell. 2011. PMID: 21565611 Free PMC article.

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The E2F1-3 transcription factors are essential for cellular proliferation.

Wu L, Timmers C, Maiti B, Saavedra HI, Sang L, Chong GT, Nuckolls F, Giangrande P, Wright FA, Field SJ, Greenberg ME, Orkin S, Nevins JR, Robinson ML, Leone G. Wu L, et al. Among authors: sang l. Nature. 2001 Nov 22;414(6862):457-62. doi: 10.1038/35106593. Nature. 2001. PMID: 11719808

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Hepatocyte nuclear factor 3 relieves chromatin-mediated repression of the alpha-fetoprotein gene.

Crowe AJ, Sang L, Li KK, Lee KC, Spear BT, Barton MC. Crowe AJ, et al. Among authors: sang l. J Biol Chem. 1999 Aug 27;274(35):25113-20. doi: 10.1074/jbc.274.35.25113. J Biol Chem. 1999. PMID: 10455192

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S-Phase progression mediates activation of a silenced gene in synthetic nuclei.

Crowe AJ, Piechan JL, Sang L, Barton MC. Crowe AJ, et al. Among authors: sang l. Mol Cell Biol. 2000 Jun;20(11):4169-80. doi: 10.1128/MCB.20.11.4169-4180.2000. Mol Cell Biol. 2000. PMID: 10805758 Free PMC article.

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Candidate exome capture identifies mutation of SDCCAG8 as the cause of a retinal-renal ciliopathy.

Otto EA, Hurd TW, Airik R, Chaki M, Zhou W, Stoetzel C, Patil SB, Levy S, Ghosh AK, Murga-Zamalloa CA, van Reeuwijk J, Letteboer SJ, Sang L, Giles RH, Liu Q, Coene KL, Estrada-Cuzcano A, Collin RW, McLaughlin HM, Held S, Kasanuki JM, Ramaswami G, Conte J, Lopez I, Washburn J, Macdonald J, Hu J, Yamashita Y, Maher ER, Guay-Woodford LM, Neumann HP, Obermüller N, Koenekoop RK, Bergmann C, Bei X, Lewis RA, Katsanis N, Lopes V, Williams DS, Lyons RH, Dang CV, Brito DA, Dias MB, Zhang X, Cavalcoli JD, Nürnberg G, Nürnberg P, Pierce EA, Jackson PK, Antignac C, Saunier S, Roepman R, Dollfus H, Khanna H, Hildebrandt F. Otto EA, et al. Among authors: sang l. Nat Genet. 2010 Oct;42(10):840-50. doi: 10.1038/ng.662. Epub 2010 Sep 12. Nat Genet. 2010. PMID: 20835237 Free PMC article.

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