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115 results
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LKB1/KRAS mutant lung cancers constitute a genetic subset of NSCLC with increased sensitivity to MAPK and mTOR signalling inhibition.
Mahoney CL, Choudhury B, Davies H, Edkins S, Greenman C, Haaften Gv, Mironenko T, Santarius T, Stevens C, Stratton MR, Futreal PA. Mahoney CL, et al. Br J Cancer. 2009 Jan 27;100(2):370-5. doi: 10.1038/sj.bjc.6604886. Br J Cancer. 2009. PMID: 19165201 Free PMC article.
Mutation analysis of 24 known cancer genes in the NCI-60 cell line set.
Ikediobi ON, Davies H, Bignell G, Edkins S, Stevens C, O'Meara S, Santarius T, Avis T, Barthorpe S, Brackenbury L, Buck G, Butler A, Clements J, Cole J, Dicks E, Forbes S, Gray K, Halliday K, Harrison R, Hills K, Hinton J, Hunter C, Jenkinson A, Jones D, Kosmidou V, Lugg R, Menzies A, Mironenko T, Parker A, Perry J, Raine K, Richardson D, Shepherd R, Small A, Smith R, Solomon H, Stephens P, Teague J, Tofts C, Varian J, Webb T, West S, Widaa S, Yates A, Reinhold W, Weinstein JN, Stratton MR, Futreal PA, Wooster R. Ikediobi ON, et al. Mol Cancer Ther. 2006 Nov;5(11):2606-12. doi: 10.1158/1535-7163.MCT-06-0433. Epub 2006 Nov 6. Mol Cancer Ther. 2006. PMID: 17088437 Free PMC article.
Identification of somatically acquired rearrangements in cancer using genome-wide massively parallel paired-end sequencing.
Campbell PJ, Stephens PJ, Pleasance ED, O'Meara S, Li H, Santarius T, Stebbings LA, Leroy C, Edkins S, Hardy C, Teague JW, Menzies A, Goodhead I, Turner DJ, Clee CM, Quail MA, Cox A, Brown C, Durbin R, Hurles ME, Edwards PA, Bignell GR, Stratton MR, Futreal PA. Campbell PJ, et al. Nat Genet. 2008 Jun;40(6):722-9. doi: 10.1038/ng.128. Epub 2008 Apr 27. Nat Genet. 2008. PMID: 18438408 Free PMC article.
Arteriovenous malformations.
Weerakkody RA, Trivedi R, Santarius T, Kirollos RW. Weerakkody RA, et al. Br J Neurosurg. 2009;23(5):494-8. doi: 10.1080/02688690802527195. Br J Neurosurg. 2009. PMID: 19701828 Review.
A census of amplified and overexpressed human cancer genes.
Santarius T, Shipley J, Brewer D, Stratton MR, Cooper CS. Santarius T, et al. Nat Rev Cancer. 2010 Jan;10(1):59-64. doi: 10.1038/nrc2771. Nat Rev Cancer. 2010. PMID: 20029424 Review.
GLO1-A novel amplified gene in human cancer.
Santarius T, Bignell GR, Greenman CD, Widaa S, Chen L, Mahoney CL, Butler A, Edkins S, Waris S, Thornalley PJ, Futreal PA, Stratton MR. Santarius T, et al. Genes Chromosomes Cancer. 2010 Aug;49(8):711-25. doi: 10.1002/gcc.20784. Genes Chromosomes Cancer. 2010. PMID: 20544845 Free PMC article.
Community consultation in emergency neurosurgical research: lessons from a proposed trial for patients with chronic subdural haematomas.
Scotton WJ, Kolias AG, Ban VS, Crick SJ, Sinha R, Gardner A, Massey K, Minett T, Santarius T, Hutchinson PJ. Scotton WJ, et al. Br J Neurosurg. 2013 Oct;27(5):590-4. doi: 10.3109/02688697.2013.793291. Epub 2013 Jun 14. Br J Neurosurg. 2013. PMID: 23767683
Diffuse cerebral vasospasm following resection of a hypoglossal schwannoma in a child.
Afshari FT, Fitzgerald JJ, Higgins JN, Garnett MR, Fernandes HM, Santarius T. Afshari FT, et al. Br J Neurosurg. 2014 Aug;28(4):541-3. doi: 10.3109/02688697.2013.865705. Epub 2013 Dec 19. Br J Neurosurg. 2014. PMID: 24350734
Processed pseudogenes acquired somatically during cancer development.
Cooke SL, Shlien A, Marshall J, Pipinikas CP, Martincorena I, Tubio JM, Li Y, Menzies A, Mudie L, Ramakrishna M, Yates L, Davies H, Bolli N, Bignell GR, Tarpey PS, Behjati S, Nik-Zainal S, Papaemmanuil E, Teixeira VH, Raine K, O'Meara S, Dodoran MS, Teague JW, Butler AP, Iacobuzio-Donahue C, Santarius T, Grundy RG, Malkin D, Greaves M, Munshi N, Flanagan AM, Bowtell D, Martin S, Larsimont D, Reis-Filho JS, Boussioutas A, Taylor JA, Hayes ND, Janes SM, Futreal PA, Stratton MR, McDermott U, Campbell PJ; ICGC Breast Cancer Group. Cooke SL, et al. Nat Commun. 2014 Apr 9;5:3644. doi: 10.1038/ncomms4644. Nat Commun. 2014. PMID: 24714652 Free PMC article.
Muscle and nerve biopsy for the neurosurgical trainee.
Hart MG, Santarius T, Trivedi RA. Hart MG, et al. Br J Neurosurg. 2013 Dec;27(6):727-34. doi: 10.3109/02688697.2013.793288. Epub 2013 May 15. Br J Neurosurg. 2013. PMID: 23675830 Review.
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