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Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy.
Farmer H, McCabe N, Lord CJ, Tutt AN, Johnson DA, Richardson TB, Santarosa M, Dillon KJ, Hickson I, Knights C, Martin NM, Jackson SP, Smith GC, Ashworth A. Farmer H, et al. Among authors: santarosa m. Nature. 2005 Apr 14;434(7035):917-21. doi: 10.1038/nature03445. Nature. 2005. PMID: 15829967
Haploinsufficiency for tumour suppressor genes: when you don't need to go all the way.
Santarosa M, Ashworth A. Santarosa M, et al. Biochim Biophys Acta. 2004 Jun 7;1654(2):105-22. doi: 10.1016/j.bbcan.2004.01.001. Biochim Biophys Acta. 2004. PMID: 15172699 Review.
BRACking news on triple-negative/basal-like breast cancers: how BRCA1 deficiency may result in the development of a selective tumor subtype.
Santarosa M, Maestro R. Santarosa M, et al. Cancer Metastasis Rev. 2012 Jun;31(1-2):131-42. doi: 10.1007/s10555-011-9336-6. Cancer Metastasis Rev. 2012. PMID: 22101651 Review.
Phenotypic features and genetic characterization of male breast cancer families: identification of two recurrent BRCA2 mutations in north-east of Italy.
Miolo G, Puppa LD, Santarosa M, De Giacomi C, Veronesi A, Bidoli E, Tibiletti MG, Viel A, Dolcetti R. Miolo G, et al. Among authors: santarosa m. BMC Cancer. 2006 Jun 9;6:156. doi: 10.1186/1471-2407-6-156. BMC Cancer. 2006. PMID: 16764716 Free PMC article.
BRCA1 modulates the expression of hnRNPA2B1 and KHSRP.
Santarosa M, Del Col L, Viel A, Bivi N, D'Ambrosio C, Scaloni A, Tell G, Maestro R. Santarosa M, et al. Cell Cycle. 2010 Dec 1;9(23):4666-73. doi: 10.4161/cc.9.23.14022. Epub 2010 Dec 1. Cell Cycle. 2010. PMID: 21099359 Free PMC article.
Mesenchymal traits are selected along with stem features in breast cancer cells grown as mammospheres.
Borgna S, Armellin M, di Gennaro A, Maestro R, Santarosa M. Borgna S, et al. Among authors: santarosa m. Cell Cycle. 2012 Nov 15;11(22):4242-51. doi: 10.4161/cc.22543. Epub 2012 Oct 24. Cell Cycle. 2012. PMID: 23095640 Free PMC article.
BRCA1 and BRCA2 genes: role in hereditary breast and ovarian cancer in Italy.
Santarosa M, Dolcetti R, Magri MD, Crivellari D, Tibiletti MG, Gallo A, Tumolo S, Della Puppa L, Furlan D, Boiocchi M, Viel A. Santarosa M, et al. Int J Cancer. 1999 Sep 24;83(1):5-9. doi: 10.1002/(sici)1097-0215(19990924)83:1<5::aid-ijc2>3.0.co;2-u. Int J Cancer. 1999. PMID: 10449599
Prognostic relevance of MLH1 and MSH2 mutations in hereditary non-polyposis colorectal cancer patients.
Russo A, Sala P, Alberici P, Gazzoli I, Radice P, Montefusco C, Torrini M, Mareni C, Fornasarig M, Santarosa M, Viel A, Benatti P, Pedroni M, de Leon MP, Lucci-Cordisco E, Genuardi M, Messerini L, Stigliano V, Cama A, Curia MC, de Lellis L, Signoroni S, Pierotti MA, Bertario L. Russo A, et al. Among authors: santarosa m. Tumori. 2009 Nov-Dec;95(6):731-8. Tumori. 2009. PMID: 20210238
Penetrances of breast and ovarian cancer in a large series of families tested for BRCA1/2 mutations.
Marroni F, Aretini P, D'Andrea E, Caligo MA, Cortesi L, Viel A, Ricevuto E, Montagna M, Cipollini G, Federico M, Santarosa M, Marchetti P, Bailey-Wilson JE, Bevilacqua G, Parmigiani G, Presciuttini S. Marroni F, et al. Among authors: santarosa m. Eur J Hum Genet. 2004 Nov;12(11):899-906. doi: 10.1038/sj.ejhg.5201256. Eur J Hum Genet. 2004. PMID: 15340362
Different expressivity of BRCA1 and BRCA2: analysis of 179 Italian pedigrees with identified mutation.
Aretini P, D'Andrea E, Pasini B, Viel A, Mariani Costantini R, Cortesi L, Ricevuto E, Agata S, Bisegna R, Boiocchi M, Caligo MA, Chieco-Bianchi L, Cipollini G, Crucianelli R, D'Amico C, Federico M, Ghimenti C, De Giacomi C, De Nicolo A, Della Puppa L, Ferrari S, Ficorella C, Iandolo D, Manoukian S, Marchetti P, Marroni F, Menin C, Montagna M, Ottini L, Pensotti V, Pierotti M, Radice P, Santarosa M, Silingardi V, Turchetti D, Bevilacqua G, Presciuttini S. Aretini P, et al. Among authors: santarosa m. Breast Cancer Res Treat. 2003 Sep;81(1):71-9. doi: 10.1023/a:1025428807472. Breast Cancer Res Treat. 2003. PMID: 14531499
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