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Human thyroid autoantigens and proteins of Yersinia and Borrelia share amino acid sequence homology that includes binding motifs to HLA-DR molecules and T-cell receptor.
Benvenga S, Santarpia L, Trimarchi F, Guarneri F. Benvenga S, et al. Among authors: santarpia l. Thyroid. 2006 Mar;16(3):225-36. doi: 10.1089/thy.2006.16.225. Thyroid. 2006. PMID: 16571084
Four patients with cutaneous metastases from medullary thyroid cancer.
Santarpia L, El-Naggar AK, Sherman SI, Hymes SR, Gagel RF, Shaw S, Sarlis NJ. Santarpia L, et al. Thyroid. 2008 Aug;18(8):901-5. doi: 10.1089/thy.2007.0179. Thyroid. 2008. PMID: 18651821
Missense mutation in the transcription factor NKX2-5: a novel molecular event in the pathogenesis of thyroid dysgenesis.
Dentice M, Cordeddu V, Rosica A, Ferrara AM, Santarpia L, Salvatore D, Chiovato L, Perri A, Moschini L, Fazzini C, Olivieri A, Costa P, Stoppioni V, Baserga M, De Felice M, Sorcini M, Fenzi G, Di Lauro R, Tartaglia M, Macchia PE. Dentice M, et al. Among authors: santarpia l. J Clin Endocrinol Metab. 2006 Apr;91(4):1428-33. doi: 10.1210/jc.2005-1350. Epub 2006 Jan 17. J Clin Endocrinol Metab. 2006. PMID: 16418214
Homologies between proteins of Borrelia burgdorferi and thyroid autoantigens.
Benvenga S, Guarneri F, Vaccaro M, Santarpia L, Trimarchi F. Benvenga S, et al. Among authors: santarpia l. Thyroid. 2004 Nov;14(11):964-6. doi: 10.1089/thy.2004.14.964. Thyroid. 2004. PMID: 15671776
Germline mutation of von Hippel-Lindau (VHL) gene 695 G>A (R161Q) in a patient with a peculiar phenotype with type 2C VHL syndrome.
Santarpia L, Lapa D, Benvenga S. Santarpia L, et al. Ann N Y Acad Sci. 2006 Aug;1073:198-202. doi: 10.1196/annals.1353.021. Ann N Y Acad Sci. 2006. PMID: 17102087
TTF-2/FOXE1 gene polymorphisms in Sicilian patients with permanent primary congenital hypothyroidism.
Santarpia L, Valenzise M, Di Pasquale G, Arrigo T, San Martino G, Cicciò MP, Trimarchi F, De Luca F, Benvenga S. Santarpia L, et al. J Endocrinol Invest. 2007 Jan;30(1):13-9. doi: 10.1007/BF03347390. J Endocrinol Invest. 2007. PMID: 17318017
The evolving field of tyrosine kinase inhibitors in the treatment of endocrine tumors.
Ye L, Santarpia L, Gagel RF. Ye L, et al. Among authors: santarpia l. Endocr Rev. 2010 Aug;31(4):578-99. doi: 10.1210/er.2009-0031. Epub 2010 Jul 6. Endocr Rev. 2010. PMID: 20605972 Review.
Genetic alterations in the RAS/RAF/mitogen-activated protein kinase and phosphatidylinositol 3-kinase/Akt signaling pathways in the follicular variant of papillary thyroid carcinoma.
Santarpia L, Myers JN, Sherman SI, Trimarchi F, Clayman GL, El-Naggar AK. Santarpia L, et al. Cancer. 2010 Jun 15;116(12):2974-83. doi: 10.1002/cncr.25061. Cancer. 2010. PMID: 20564403
Targeted therapy for endocrine cancer: the medullary thyroid carcinoma paradigm.
Ye L, Santarpia L, Gagel RF. Ye L, et al. Among authors: santarpia l. Endocr Pract. 2009 Sep-Oct;15(6):597-604. doi: 10.4158/EP09148.RAR. Endocr Pract. 2009. PMID: 19546050 Review.
Detection and molecular characterization of a novel BRAF activated domain mutation in follicular variant of papillary thyroid carcinoma.
Santarpia L, Sherman SI, Marabotti A, Clayman GL, El-Naggar AK. Santarpia L, et al. Hum Pathol. 2009 Jun;40(6):827-33. doi: 10.1016/j.humpath.2008.11.003. Epub 2009 Feb 5. Hum Pathol. 2009. PMID: 19200582
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