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CNK3 and IPCEF1 produce a single protein that is required for HGF dependent Arf6 activation and migration.
Attar MA, Salem JC, Pursel HS, Santy LC. Attar MA, et al. Among authors: santy lc. Exp Cell Res. 2012 Feb 1;318(3):228-37. doi: 10.1016/j.yexcr.2011.10.018. Epub 2011 Nov 7. Exp Cell Res. 2012. PMID: 22085542
ARF GTPases and their GEFs and GAPs: concepts and challenges.
Sztul E, Chen PW, Casanova JE, Cherfils J, Dacks JB, Lambright DG, Lee FS, Randazzo PA, Santy LC, Schürmann A, Wilhelmi I, Yohe ME, Kahn RA. Sztul E, et al. Among authors: santy lc. Mol Biol Cell. 2019 May 15;30(11):1249-1271. doi: 10.1091/mbc.E18-12-0820. Mol Biol Cell. 2019. PMID: 31084567 Free PMC article. Review.
ARF-GEF cytohesin-2/ARNO regulates R-Ras and α5-integrin recycling through an EHD1-positive compartment.
Salem JC, Reviriego-Mendoza MM, Santy LC. Salem JC, et al. Among authors: santy lc. Mol Biol Cell. 2015 Nov 15;26(23):4265-79. doi: 10.1091/mbc.E15-05-0278. Epub 2015 Sep 16. Mol Biol Cell. 2015. PMID: 26378252 Free PMC article.
The cytohesin guanosine exchange factors (GEFs) are required to promote HGF-mediated renal recovery after acute kidney injury (AKI) in mice.
Reviriego-Mendoza MM, Santy LC. Reviriego-Mendoza MM, et al. Among authors: santy lc. Physiol Rep. 2015 Jun;3(6):e12442. doi: 10.14814/phy2.12442. Physiol Rep. 2015. PMID: 26116550 Free PMC article.
The cytohesin coiled-coil domain interacts with threonine 276 to control membrane association.
Hiester KG, Santy LC. Hiester KG, et al. Among authors: santy lc. PLoS One. 2013 Nov 26;8(11):e82084. doi: 10.1371/journal.pone.0082084. eCollection 2013. PLoS One. 2013. PMID: 24303080 Free PMC article.
Phosphoinositide specificity determines which cytohesins regulate β1 integrin recycling.
Oh SJ, Santy LC. Oh SJ, et al. Among authors: santy lc. J Cell Sci. 2012 Jul 1;125(Pt 13):3195-201. doi: 10.1242/jcs.101683. Epub 2012 Mar 27. J Cell Sci. 2012. PMID: 22454518 Free article.
Differential effects of cytohesins 2 and 3 on beta1 integrin recycling.
Oh SJ, Santy LC. Oh SJ, et al. Among authors: santy lc. J Biol Chem. 2010 May 7;285(19):14610-6. doi: 10.1074/jbc.M109.043935. Epub 2010 Mar 11. J Biol Chem. 2010. PMID: 20223830 Free PMC article.
ARF1 and ARF6 regulate recycling of GRASP/Tamalin and the Rac1-GEF Dock180 during HGF-induced Rac1 activation.
Koubek EJ, Santy LC. Koubek EJ, et al. Among authors: santy lc. Small GTPases. 2018 May 4;9(3):242-259. doi: 10.1080/21541248.2016.1219186. Epub 2016 Aug 26. Small GTPases. 2018. PMID: 27562622 Free PMC article.
The scaffolding protein GRASP/Tamalin directly binds to Dock180 as well as to cytohesins facilitating GTPase crosstalk in epithelial cell migration.
Attar MA, Santy LC. Attar MA, et al. Among authors: santy lc. BMC Cell Biol. 2013 Feb 26;14:9. doi: 10.1186/1471-2121-14-9. BMC Cell Biol. 2013. PMID: 23441967 Free PMC article.
GRASP and IPCEF promote ARF-to-Rac signaling and cell migration by coordinating the association of ARNO/cytohesin 2 with Dock180.
White DT, McShea KM, Attar MA, Santy LC. White DT, et al. Among authors: santy lc. Mol Biol Cell. 2010 Feb 15;21(4):562-71. doi: 10.1091/mbc.e09-03-0217. Epub 2009 Dec 16. Mol Biol Cell. 2010. PMID: 20016009 Free PMC article.
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