Sanz LA - Search Results

1

Genome-wide DNA hypomethylation and RNA:DNA hybrid accumulation in Aicardi-Goutières syndrome.

Lim YW, Sanz LA, Xu X, Hartono SR, Chédin F. Lim YW, et al. Among authors: sanz la. Elife. 2015 Jul 16;4:e08007. doi: 10.7554/eLife.08007. Elife. 2015. PMID: 26182405 Free PMC article.

2

Transcription-associated R-loop formation across the human FMR1 CGG-repeat region.

Loomis EW, Sanz LA, Chédin F, Hagerman PJ. Loomis EW, et al. Among authors: sanz la. PLoS Genet. 2014 Apr 17;10(4):e1004294. doi: 10.1371/journal.pgen.1004294. eCollection 2014 Apr. PLoS Genet. 2014. PMID: 24743386 Free PMC article.

3

Prevalent, Dynamic, and Conserved R-Loop Structures Associate with Specific Epigenomic Signatures in Mammals.

Sanz LA, Hartono SR, Lim YW, Steyaert S, Rajpurkar A, Ginno PA, Xu X, Chédin F. Sanz LA, et al. Mol Cell. 2016 Jul 7;63(1):167-78. doi: 10.1016/j.molcel.2016.05.032. Epub 2016 Jun 30. Mol Cell. 2016. PMID: 27373332 Free PMC article.

4

Co-transcriptional R-loops are the main cause of estrogen-induced DNA damage.

Stork CT, Bocek M, Crossley MP, Sollier J, Sanz LA, Chédin F, Swigut T, Cimprich KA. Stork CT, et al. Among authors: sanz la. Elife. 2016 Aug 23;5:e17548. doi: 10.7554/eLife.17548. Elife. 2016. PMID: 27552054 Free PMC article.

5

DNA Topoisomerase I differentially modulates R-loops across the human genome.

Manzo SG, Hartono SR, Sanz LA, Marinello J, De Biasi S, Cossarizza A, Capranico G, Chedin F. Manzo SG, et al. Among authors: sanz la. Genome Biol. 2018 Jul 30;19(1):100. doi: 10.1186/s13059-018-1478-1. Genome Biol. 2018. PMID: 30060749 Free PMC article.

6

High-resolution, strand-specific R-loop mapping via S9.6-based DNA-RNA immunoprecipitation and high-throughput sequencing.

Sanz LA, Chédin F. Sanz LA, et al. Nat Protoc. 2019 Jun;14(6):1734-1755. doi: 10.1038/s41596-019-0159-1. Epub 2019 May 3. Nat Protoc. 2019. PMID: 31053798 Free PMC article.

7

Ultra-deep Coverage Single-molecule R-loop Footprinting Reveals Principles of R-loop Formation.

Malig M, Hartono SR, Giafaglione JM, Sanz LA, Chedin F. Malig M, et al. Among authors: sanz la. J Mol Biol. 2020 Mar 27;432(7):2271-2288. doi: 10.1016/j.jmb.2020.02.014. Epub 2020 Feb 24. J Mol Biol. 2020. PMID: 32105733 Free PMC article.

8

RNA-DNA strand exchange by the Drosophila Polycomb complex PRC2.

Alecki C, Chiwara V, Sanz LA, Grau D, Arias Pérez O, Boulier EL, Armache KJ, Chédin F, Francis NJ. Alecki C, et al. Among authors: sanz la. Nat Commun. 2020 Apr 14;11(1):1781. doi: 10.1038/s41467-020-15609-x. Nat Commun. 2020. PMID: 32286294 Free PMC article.

9

SETX (senataxin), the helicase mutated in AOA2 and ALS4, functions in autophagy regulation.

Richard P, Feng S, Tsai YL, Li W, Rinchetti P, Muhith U, Irizarry-Cole J, Stolz K, Sanz LA, Hartono S, Hoque M, Tadesse S, Seitz H, Lotti F, Hirano M, Chédin F, Tian B, Manley JL. Richard P, et al. Among authors: sanz la. Autophagy. 2021 Aug;17(8):1889-1906. doi: 10.1080/15548627.2020.1796292. Epub 2020 Aug 7. Autophagy. 2021. PMID: 32686621 Free PMC article.

10

Topoisomerase 1 prevents replication stress at R-loop-enriched transcription termination sites.

Promonet A, Padioleau I, Liu Y, Sanz L, Biernacka A, Schmitz AL, Skrzypczak M, Sarrazin A, Mettling C, Rowicka M, Ginalski K, Chedin F, Chen CL, Lin YL, Pasero P. Promonet A, et al. Nat Commun. 2020 Aug 7;11(1):3940. doi: 10.1038/s41467-020-17858-2. Nat Commun. 2020. PMID: 32769985 Free PMC article.

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