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133 results
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Interleukin-8 receptor antagonists in pulmonary diseases.
Hay DW, Sarau HM. Hay DW, et al. Among authors: sarau hm. Curr Opin Pharmacol. 2001 Jun;1(3):242-7. doi: 10.1016/s1471-4892(01)00043-1. Curr Opin Pharmacol. 2001. PMID: 11712746 Review.
Cloning and pharmacological characterization of the cat urotensin-II receptor (UT).
Aiyar N, Johns DG, Ao Z, Disa J, Behm DJ, Foley JJ, Buckley PT, Sarau HM, van-der-Keyl HK, Elshourbagy NA, Douglas SA. Aiyar N, et al. Among authors: sarau hm. Biochem Pharmacol. 2005 Apr 1;69(7):1069-79. doi: 10.1016/j.bcp.2004.12.016. Biochem Pharmacol. 2005. PMID: 15763543
Radioligand binding and functional characterization of recombinant human NmU1 and NmU2 receptors stably expressed in clonal human embryonic kidney-293 cells.
Aiyar N, Disa J, Foley JJ, Buckley PT, Wixted WE, Pullen M, Shabon U, Dul E, Szekeres PG, Elshourbagy NA, Sarau HM, Appelbaum E, Bolaky J. Aiyar N, et al. Among authors: sarau hm. Pharmacology. 2004 Sep;72(1):33-41. doi: 10.1159/000078630. Pharmacology. 2004. PMID: 15292653
Nonpeptidic urotensin-II receptor antagonists I: in vitro pharmacological characterization of SB-706375.
Douglas SA, Behm DJ, Aiyar NV, Naselsky D, Disa J, Brooks DP, Ohlstein EH, Gleason JG, Sarau HM, Foley JJ, Buckley PT, Schmidt DB, Wixted WE, Widdowson K, Riley G, Jin J, Gallagher TF, Schmidt SJ, Ridgers L, Christmann LT, Keenan RM, Knight SD, Dhanak D. Douglas SA, et al. Among authors: sarau hm. Br J Pharmacol. 2005 Jul;145(5):620-35. doi: 10.1038/sj.bjp.0706229. Br J Pharmacol. 2005. PMID: 15852036 Free PMC article.
Discovery of potent and orally bioavailable N,N'-diarylurea antagonists for the CXCR2 chemokine receptor.
Jin Q, Nie H, McCleland BW, Widdowson KL, Palovich MR, Elliott JD, Goodman RM, Burman M, Sarau HM, Ward KW, Nord M, Orr BM, Gorycki PD, Busch-Petersen J. Jin Q, et al. Among authors: sarau hm. Bioorg Med Chem Lett. 2004 Sep 6;14(17):4375-8. doi: 10.1016/j.bmcl.2004.06.097. Bioorg Med Chem Lett. 2004. PMID: 15357956
Regulation of TNF-alpha- and IFN-gamma-induced CXCL10 expression: participation of the airway smooth muscle in the pulmonary inflammatory response in chronic obstructive pulmonary disease.
Hardaker EL, Bacon AM, Carlson K, Roshak AK, Foley JJ, Schmidt DB, Buckley PT, Comegys M, Panettieri RA Jr, Sarau HM, Belmonte KE. Hardaker EL, et al. Among authors: sarau hm. FASEB J. 2004 Jan;18(1):191-3. doi: 10.1096/fj.03-0170fje. Epub 2003 Nov 3. FASEB J. 2004. PMID: 14597565
The neuromedin B receptor antagonist, BIM-23127, is a potent antagonist at human and rat urotensin-II receptors.
Herold CL, Behm DJ, Buckley PT, Foley JJ, Wixted WE, Sarau HM, Douglas SA. Herold CL, et al. Among authors: sarau hm. Br J Pharmacol. 2003 May;139(2):203-7. doi: 10.1038/sj.bjp.0705251. Br J Pharmacol. 2003. PMID: 12770925 Free PMC article.
Nonpeptide tachykinin receptor antagonists. III. SB 235375, a low central nervous system-penetrant, potent and selective neurokinin-3 receptor antagonist, inhibits citric acid-induced cough and airways hyper-reactivity in guinea pigs.
Hay DW, Giardina GA, Griswold DE, Underwood DC, Kotzer CJ, Bush B, Potts W, Sandhu P, Lundberg D, Foley JJ, Schmidt DB, Martin LD, Kilian D, Legos JJ, Barone FC, Luttmann MA, Grugni M, Raveglia LF, Sarau HM. Hay DW, et al. Among authors: sarau hm. J Pharmacol Exp Ther. 2002 Jan;300(1):314-23. doi: 10.1124/jpet.300.1.314. J Pharmacol Exp Ther. 2002. PMID: 11752131
A potent and selective nonpeptide antagonist of CXCR2 inhibits acute and chronic models of arthritis in the rabbit.
Podolin PL, Bolognese BJ, Foley JJ, Schmidt DB, Buckley PT, Widdowson KL, Jin Q, White JR, Lee JM, Goodman RB, Hagen TR, Kajikawa O, Marshall LA, Hay DW, Sarau HM. Podolin PL, et al. Among authors: sarau hm. J Immunol. 2002 Dec 1;169(11):6435-44. doi: 10.4049/jimmunol.169.11.6435. J Immunol. 2002. PMID: 12444152
Pharmacological characterization of GSK573719 (umeclidinium): a novel, long-acting, inhaled antagonist of the muscarinic cholinergic receptors for treatment of pulmonary diseases.
Salmon M, Luttmann MA, Foley JJ, Buckley PT, Schmidt DB, Burman M, Webb EF, DeHaas CJ, Kotzer CJ, Barrett VJ, Slack RJ, Sarau HM, Palovich MR, Lainé DI, Hay DW, Rumsey WL. Salmon M, et al. Among authors: sarau hm. J Pharmacol Exp Ther. 2013 May;345(2):260-70. doi: 10.1124/jpet.112.202051. Epub 2013 Feb 22. J Pharmacol Exp Ther. 2013. PMID: 23435542
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