Sardana V - Search Results

1

Inhibition of a mitotic motor protein: where, how, and conformational consequences.

Yan Y, Sardana V, Xu B, Homnick C, Halczenko W, Buser CA, Schaber M, Hartman GD, Huber HE, Kuo LC. Yan Y, et al. Among authors: sardana v. J Mol Biol. 2004 Jan 9;335(2):547-54. doi: 10.1016/j.jmb.2003.10.074. J Mol Biol. 2004. PMID: 14672662

2

X-ray structure of simian immunodeficiency virus integrase containing the core and C-terminal domain (residues 50-293)--an initial glance of the viral DNA binding platform.

Chen Z, Yan Y, Munshi S, Li Y, Zugay-Murphy J, Xu B, Witmer M, Felock P, Wolfe A, Sardana V, Emini EA, Hazuda D, Kuo LC. Chen Z, et al. Among authors: sardana v. J Mol Biol. 2000 Feb 18;296(2):521-33. doi: 10.1006/jmbi.1999.3451. J Mol Biol. 2000. PMID: 10669606

3

Development of 6-substituted indolylquinolinones as potent Chek1 kinase inhibitors.

Huang S, Garbaccio RM, Fraley ME, Steen J, Kreatsoulas C, Hartman G, Stirdivant S, Drakas B, Rickert K, Walsh E, Hamilton K, Buser CA, Hardwick J, Mao X, Abrams M, Beck S, Tao W, Lobell R, Sepp-Lorenzino L, Yan Y, Ikuta M, Murphy JZ, Sardana V, Munshi S, Kuo L, Reilly M, Mahan E. Huang S, et al. Among authors: sardana v. Bioorg Med Chem Lett. 2006 Nov 15;16(22):5907-12. doi: 10.1016/j.bmcl.2006.08.053. Epub 2006 Sep 20. Bioorg Med Chem Lett. 2006. PMID: 16990002

4

Development of thioquinazolinones, allosteric Chk1 kinase inhibitors.

Converso A, Hartingh T, Garbaccio RM, Tasber E, Rickert K, Fraley ME, Yan Y, Kreatsoulas C, Stirdivant S, Drakas B, Walsh ES, Hamilton K, Buser CA, Mao X, Abrams MT, Beck SC, Tao W, Lobell R, Sepp-Lorenzino L, Zugay-Murphy J, Sardana V, Munshi SK, Jezequel-Sur SM, Zuck PD, Hartman GD. Converso A, et al. Among authors: sardana v. Bioorg Med Chem Lett. 2009 Feb 15;19(4):1240-4. doi: 10.1016/j.bmcl.2008.12.076. Epub 2008 Dec 24. Bioorg Med Chem Lett. 2009. PMID: 19155174

5

Structural basis for the inhibition of RNase H activity of HIV-1 reverse transcriptase by RNase H active site-directed inhibitors.

Su HP, Yan Y, Prasad GS, Smith RF, Daniels CL, Abeywickrema PD, Reid JC, Loughran HM, Kornienko M, Sharma S, Grobler JA, Xu B, Sardana V, Allison TJ, Williams PD, Darke PL, Hazuda DJ, Munshi S. Su HP, et al. Among authors: sardana v. J Virol. 2010 Aug;84(15):7625-33. doi: 10.1128/JVI.00353-10. Epub 2010 May 19. J Virol. 2010. PMID: 20484498 Free PMC article.

6

Complex of NS3 protease and NS4A peptide of BK strain hepatitis C virus: a 2.2 A resolution structure in a hexagonal crystal form.

Yan Y, Li Y, Munshi S, Sardana V, Cole JL, Sardana M, Steinkuehler C, Tomei L, De Francesco R, Kuo LC, Chen Z. Yan Y, et al. Among authors: sardana m, sardana v. Protein Sci. 1998 Apr;7(4):837-47. doi: 10.1002/pro.5560070402. Protein Sci. 1998. PMID: 9568891 Free PMC article.

7

A general procedure for the purification of human beta-secretase expressed in Escherichia coli.

Sardana V, Xu B, Zugay-Murphy J, Chen Z, Sardana M, Darke PL, Munshi S, Kuo LC. Sardana V, et al. Among authors: sardana m. Protein Expr Purif. 2004 Apr;34(2):190-6. doi: 10.1016/j.pep.2003.12.014. Protein Expr Purif. 2004. PMID: 15003250

8

Identification of a small molecule nonpeptide active site beta-secretase inhibitor that displays a nontraditional binding mode for aspartyl proteases.

Coburn CA, Stachel SJ, Li YM, Rush DM, Steele TG, Chen-Dodson E, Holloway MK, Xu M, Huang Q, Lai MT, DiMuzio J, Crouthamel MC, Shi XP, Sardana V, Chen Z, Munshi S, Kuo L, Makara GM, Annis DA, Tadikonda PK, Nash HM, Vacca JP, Wang T. Coburn CA, et al. Among authors: sardana v. J Med Chem. 2004 Dec 2;47(25):6117-9. doi: 10.1021/jm049388p. J Med Chem. 2004. PMID: 15566281

9

Purification, solution properties and crystallization of SIV integrase containing a continuous core and C-terminal domain.

Li Y, Yan Y, Zugay-Murphy J, Xu B, Cole JL, Witmer M, Felock P, Wolfe A, Hazuda D, Sardana MK, Chen Z, Kuo LC, Sardana VV. Li Y, et al. Among authors: sardana mk, sardana vv. Acta Crystallogr D Biol Crystallogr. 1999 Nov;55(Pt 11):1906-10. doi: 10.1107/s0907444999009610. Acta Crystallogr D Biol Crystallogr. 1999. PMID: 10531491

10

An uniquely purified HCV NS3 protease and NS4A(21-34) peptide form a highly active serine protease complex in peptide hydrolysis.

Sardana VV, Blue JT, Zugay-Murphy J, Sardana MK, Kuo LC. Sardana VV, et al. Among authors: sardana mk. Protein Expr Purif. 1999 Aug;16(3):440-7. doi: 10.1006/prep.1999.1090. Protein Expr Purif. 1999. PMID: 10425166

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