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AKT modulates the autophagy-lysosome pathway via TFEB.
Palmieri M, Pal R, Sardiello M. Palmieri M, et al. Cell Cycle. 2017 Jul 3;16(13):1237-1238. doi: 10.1080/15384101.2017.1337968. Epub 2017 Jun 21. Cell Cycle. 2017. PMID: 28636416 Free PMC article. No abstract available.
CLUH regulates mitochondrial biogenesis by binding mRNAs of nuclear-encoded mitochondrial proteins.
Gao J, Schatton D, Martinelli P, Hansen H, Pla-Martin D, Barth E, Becker C, Altmueller J, Frommolt P, Sardiello M, Rugarli EI. Gao J, et al. J Cell Biol. 2014 Oct 27;207(2):213-23. doi: 10.1083/jcb.201403129. J Cell Biol. 2014. PMID: 25349259 Free PMC article.
Diminished MTORC1-Dependent JNK Activation Underlies the Neurodevelopmental Defects Associated with Lysosomal Dysfunction.
Wong CO, Palmieri M, Li J, Akhmedov D, Chao Y, Broadhead GT, Zhu MX, Berdeaux R, Collins CA, Sardiello M, Venkatachalam K. Wong CO, et al. Cell Rep. 2015 Sep 29;12(12):2009-20. doi: 10.1016/j.celrep.2015.08.047. Epub 2015 Sep 17. Cell Rep. 2015. PMID: 26387958 Free PMC article.
mTORC1-independent TFEB activation via Akt inhibition promotes cellular clearance in neurodegenerative storage diseases.
Palmieri M, Pal R, Nelvagal HR, Lotfi P, Stinnett GR, Seymour ML, Chaudhury A, Bajaj L, Bondar VV, Bremner L, Saleem U, Tse DY, Sanagasetti D, Wu SM, Neilson JR, Pereira FA, Pautler RG, Rodney GG, Cooper JD, Sardiello M. Palmieri M, et al. Nat Commun. 2017 Feb 6;8:14338. doi: 10.1038/ncomms14338. Nat Commun. 2017. PMID: 28165011 Free PMC article.
Lysosomes and Brain Health.
Sharma J, di Ronza A, Lotfi P, Sardiello M. Sharma J, et al. Among authors: sardiello m. Annu Rev Neurosci. 2018 Jul 8;41:255-276. doi: 10.1146/annurev-neuro-080317-061804. Epub 2018 Apr 16. Annu Rev Neurosci. 2018. PMID: 29661037 Review.
Lysosome biogenesis in health and disease.
Bajaj L, Lotfi P, Pal R, Ronza AD, Sharma J, Sardiello M. Bajaj L, et al. Among authors: sardiello m. J Neurochem. 2019 Mar;148(5):573-589. doi: 10.1111/jnc.14564. Epub 2018 Oct 18. J Neurochem. 2019. PMID: 30092616 Free PMC article. Review.
TFEB enhances astroglial uptake of extracellular tau species and reduces tau spreading.
Martini-Stoica H, Cole AL, Swartzlander DB, Chen F, Wan YW, Bajaj L, Bader DA, Lee VMY, Trojanowski JQ, Liu Z, Sardiello M, Zheng H. Martini-Stoica H, et al. Among authors: sardiello m. J Exp Med. 2018 Sep 3;215(9):2355-2377. doi: 10.1084/jem.20172158. Epub 2018 Aug 14. J Exp Med. 2018. PMID: 30108137 Free PMC article.
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