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NOX2 complex-derived ROS as immune regulators.
Sareila O, Kelkka T, Pizzolla A, Hultqvist M, Holmdahl R. Sareila O, et al. Antioxid Redox Signal. 2011 Oct 15;15(8):2197-208. doi: 10.1089/ars.2010.3635. Epub 2011 Apr 11. Antioxid Redox Signal. 2011. PMID: 20919938 Review.
The Macrophage Mannose Receptor Regulate Mannan-Induced Psoriasis, Psoriatic Arthritis, and Rheumatoid Arthritis-Like Disease Models.
Hagert C, Sareila O, Kelkka T, Jalkanen S, Holmdahl R. Hagert C, et al. Among authors: sareila o. Front Immunol. 2018 Feb 6;9:114. doi: 10.3389/fimmu.2018.00114. eCollection 2018. Front Immunol. 2018. PMID: 29467756 Free PMC article.
Reactive Oxygen Species Regulate Both Priming and Established Arthritis, but with Different Mechanisms.
Sareila O, Hagert C, Kelkka T, Linja M, Xu B, Kihlberg J, Holmdahl R. Sareila O, et al. Antioxid Redox Signal. 2017 Dec 20;27(18):1473-1490. doi: 10.1089/ars.2016.6981. Epub 2017 Jun 1. Antioxid Redox Signal. 2017. PMID: 28467721
Ncf1 polymorphism reveals oxidative regulation of autoimmune chronic inflammation.
Holmdahl R, Sareila O, Olsson LM, Bäckdahl L, Wing K. Holmdahl R, et al. Among authors: sareila o. Immunol Rev. 2016 Jan;269(1):228-47. doi: 10.1111/imr.12378. Immunol Rev. 2016. PMID: 26683156 Review.
Reactive oxygen species deficiency induces autoimmunity with type 1 interferon signature.
Kelkka T, Kienhöfer D, Hoffmann M, Linja M, Wing K, Sareila O, Hultqvist M, Laajala E, Chen Z, Vasconcelos J, Neves E, Guedes M, Marques L, Krönke G, Helminen M, Kainulainen L, Olofsson P, Jalkanen S, Lahesmaa R, Souto-Carneiro MM, Holmdahl R. Kelkka T, et al. Among authors: sareila o. Antioxid Redox Signal. 2014 Dec 1;21(16):2231-45. doi: 10.1089/ars.2013.5828. Epub 2014 Jul 29. Antioxid Redox Signal. 2014. PMID: 24787605 Free PMC article.
Identification of a region in p47phox/NCF1 crucial for phagocytic NADPH oxidase (NOX2) activation.
Sareila O, Jaakkola N, Olofsson P, Kelkka T, Holmdahl R. Sareila O, et al. J Leukoc Biol. 2013 Mar;93(3):427-35. doi: 10.1189/jlb.1211588. Epub 2012 Dec 27. J Leukoc Biol. 2013. PMID: 23271700 Free PMC article.
Hydrogen peroxide as an immunological transmitter regulating autoreactive T cells.
Holmdahl R, Sareila O, Pizzolla A, Winter S, Hagert C, Jaakkola N, Kelkka T, Olsson LM, Wing K, Bäckdahl L. Holmdahl R, et al. Among authors: sareila o. Antioxid Redox Signal. 2013 Apr 20;18(12):1463-74. doi: 10.1089/ars.2012.4734. Epub 2012 Aug 17. Antioxid Redox Signal. 2013. PMID: 22900704 Review.
Superoxide dismutase 3 limits collagen-induced arthritis in the absence of phagocyte oxidative burst.
Kelkka T, Laurila JP, Sareila O, Olofsson P, Laukkanen MO, Holmdahl R. Kelkka T, et al. Among authors: sareila o. Mediators Inflamm. 2012;2012:730469. doi: 10.1155/2012/730469. Epub 2012 Mar 5. Mediators Inflamm. 2012. PMID: 22529530 Free PMC article.
Positioning of a polymorphic quantitative trait nucleotide in the Ncf1 gene controlling oxidative burst response and arthritis severity in rats.
Hultqvist M, Sareila O, Vilhardt F, Norin U, Olsson LM, Olofsson P, Hellman U, Holmdahl R. Hultqvist M, et al. Among authors: sareila o. Antioxid Redox Signal. 2011 Jun 15;14(12):2373-83. doi: 10.1089/ars.2010.3440. Epub 2011 Mar 31. Antioxid Redox Signal. 2011. PMID: 21275845
In vivo imaging of reactive oxygen and nitrogen species in murine colitis.
Asghar MN, Emani R, Alam C, Helenius TO, Grönroos TJ, Sareila O, Din MU, Holmdahl R, Hänninen A, Toivola DM. Asghar MN, et al. Among authors: sareila o. Inflamm Bowel Dis. 2014 Aug;20(8):1435-47. doi: 10.1097/MIB.0000000000000118. Inflamm Bowel Dis. 2014. PMID: 24983980
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