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65 results
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Presence of homozygous KIT exon 11 mutations is strongly associated with malignant clinical behavior in gastrointestinal stromal tumors.
Lasota J, vel Dobosz AJ, Wasag B, Wozniak A, Kraszewska E, Michej W, Ptaszynski K, Rutkowski P, Sarlomo-Rikala M, Steigen SE, Schneider-Stock R, Stachura J, Chosia M, Ogun G, Ruka W, Siedlecki JA, Miettinen M. Lasota J, et al. Lab Invest. 2007 Oct;87(10):1029-41. doi: 10.1038/labinvest.3700628. Epub 2007 Jul 16. Lab Invest. 2007. PMID: 17632543
KIT 1530ins6 mutation defines a subset of predominantly malignant gastrointestinal stromal tumors of intestinal origin.
Lasota J, Kopczynski J, Sarlomo-Rikala M, Schneider-Stock R, Stachura T, Kordek R, Michal M, Boltze C, Roessner A, Stachura J, Miettinen M. Lasota J, et al. Hum Pathol. 2003 Dec;34(12):1306-12. doi: 10.1016/s0046-8177(03)00407-6. Hum Pathol. 2003. PMID: 14691917
Gastrointestinal stromal tumors with internal tandem duplications in 3' end of KIT juxtamembrane domain occur predominantly in stomach and generally seem to have a favorable course.
Lasota J, Dansonka-Mieszkowska A, Stachura T, Schneider-Stock R, Kallajoki M, Steigen SE, Sarlomo-Rikala M, Boltze C, Kordek R, Roessner A, Stachura J, Miettinen M. Lasota J, et al. Mod Pathol. 2003 Dec;16(12):1257-64. doi: 10.1097/01.MP.0000097365.72526.3E. Mod Pathol. 2003. PMID: 14681327
Chromosome 22q alterations and expression of the NF2 gene product, merlin, in gastrointestinal stromal tumors.
Pylkkänen L, Sarlomo-Rikala M, Wessman M, Hämäläinen E, Sainio M, Husgafvel-Pursiainen K, Carpén O. Pylkkänen L, et al. Hum Pathol. 2003 Sep;34(9):872-9. doi: 10.1016/s0046-8177(03)00349-6. Hum Pathol. 2003. PMID: 14562282
Gastrointestinal stromal tumors, intramural leiomyomas, and leiomyosarcomas in the duodenum: a clinicopathologic, immunohistochemical, and molecular genetic study of 167 cases.
Miettinen M, Kopczynski J, Makhlouf HR, Sarlomo-Rikala M, Gyorffy H, Burke A, Sobin LH, Lasota J. Miettinen M, et al. Am J Surg Pathol. 2003 May;27(5):625-41. doi: 10.1097/00000478-200305000-00006. Am J Surg Pathol. 2003. PMID: 12717247
SLUG transcription factor: a pro-survival and prognostic factor in gastrointestinal stromal tumour.
Pulkka OP, Nilsson B, Sarlomo-Rikala M, Reichardt P, Eriksson M, Hall KS, Wardelmann E, Vehtari A, Joensuu H, Sihto H. Pulkka OP, et al. Among authors: sarlomo rikala m. Br J Cancer. 2017 Apr 25;116(9):1195-1202. doi: 10.1038/bjc.2017.82. Epub 2017 Mar 23. Br J Cancer. 2017. PMID: 28334729 Free PMC article.
Frequency and clinicopathologic profile of PIK3CA mutant GISTs: molecular genetic study of 529 cases.
Lasota J, Felisiak-Golabek A, Wasag B, Kowalik A, Zięba S, Chłopek M, Wang ZF, Coates T, Kopczynski J, Gozdz S, Sarlomo-Rikala M, Miettinen M. Lasota J, et al. Among authors: sarlomo rikala m. Mod Pathol. 2016 Mar;29(3):275-82. doi: 10.1038/modpathol.2015.160. Epub 2016 Jan 22. Mod Pathol. 2016. PMID: 26796526 Free article.
Risk factors for gastrointestinal stromal tumor recurrence in patients treated with adjuvant imatinib.
Joensuu H, Eriksson M, Hall KS, Hartmann JT, Pink D, Schütte J, Ramadori G, Hohenberger P, Duyster J, Al-Batran SE, Schlemmer M, Bauer S, Wardelmann E, Sarlomo-Rikala M, Nilsson B, Sihto H, Ballman KV, Leinonen M, DeMatteo RP, Reichardt P. Joensuu H, et al. Among authors: sarlomo rikala m. Cancer. 2014 Aug 1;120(15):2325-33. doi: 10.1002/cncr.28669. Epub 2014 Apr 15. Cancer. 2014. PMID: 24737415 Free PMC article. Clinical Trial.
One vs three years of adjuvant imatinib for operable gastrointestinal stromal tumor: a randomized trial.
Joensuu H, Eriksson M, Sundby Hall K, Hartmann JT, Pink D, Schütte J, Ramadori G, Hohenberger P, Duyster J, Al-Batran SE, Schlemmer M, Bauer S, Wardelmann E, Sarlomo-Rikala M, Nilsson B, Sihto H, Monge OR, Bono P, Kallio R, Vehtari A, Leinonen M, Alvegård T, Reichardt P. Joensuu H, et al. JAMA. 2012 Mar 28;307(12):1265-72. doi: 10.1001/jama.2012.347. JAMA. 2012. PMID: 22453568 Clinical Trial.
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