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Bisphosphonated fluoroquinolone esters as osteotropic prodrugs for the prevention of osteomyelitis.
Tanaka KS, Houghton TJ, Kang T, Dietrich E, Delorme D, Ferreira SS, Caron L, Viens F, Arhin FF, Sarmiento I, Lehoux D, Fadhil I, Laquerre K, Liu J, Ostiguy V, Poirier H, Moeck G, Parr TR Jr, Rafai Far A. Tanaka KS, et al. Among authors: sarmiento i. Bioorg Med Chem. 2008 Oct 15;16(20):9217-29. doi: 10.1016/j.bmc.2008.09.010. Epub 2008 Sep 9. Bioorg Med Chem. 2008. PMID: 18815051
Linking bisphosphonates to the free amino groups in fluoroquinolones: preparation of osteotropic prodrugs for the prevention of osteomyelitis.
Houghton TJ, Tanaka KS, Kang T, Dietrich E, Lafontaine Y, Delorme D, Ferreira SS, Viens F, Arhin FF, Sarmiento I, Lehoux D, Fadhil I, Laquerre K, Liu J, Ostiguy V, Poirier H, Moeck G, Parr TR Jr, Far AR. Houghton TJ, et al. Among authors: sarmiento i. J Med Chem. 2008 Nov 13;51(21):6955-69. doi: 10.1021/jm801007z. Epub 2008 Oct 4. J Med Chem. 2008. PMID: 18834106
Triaminotriazine DNA helicase inhibitors with antibacterial activity.
McKay GA, Reddy R, Arhin F, Belley A, Lehoux D, Moeck G, Sarmiento I, Parr TR, Gros P, Pelletier J, Far AR. McKay GA, et al. Among authors: sarmiento i. Bioorg Med Chem Lett. 2006 Mar 1;16(5):1286-90. doi: 10.1016/j.bmcl.2005.11.076. Epub 2005 Dec 15. Bioorg Med Chem Lett. 2006. PMID: 16343901
Assessment of oritavancin serum protein binding across species.
Arhin FF, Belley A, McKay G, Beaulieu S, Sarmiento I, Parr TR Jr, Moeck G. Arhin FF, et al. Among authors: sarmiento i. Antimicrob Agents Chemother. 2010 Aug;54(8):3481-3. doi: 10.1128/AAC.00271-10. Epub 2010 May 24. Antimicrob Agents Chemother. 2010. PMID: 20498314 Free PMC article.
85 results