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The many faces of the origin recognition complex.
Sasaki T, Gilbert DM. Sasaki T, et al. Curr Opin Cell Biol. 2007 Jun;19(3):337-43. doi: 10.1016/j.ceb.2007.04.007. Epub 2007 Apr 26. Curr Opin Cell Biol. 2007. PMID: 17466500 Review.
Pre-replication complex proteins assemble at regions of low nucleosome occupancy within the Chinese hamster dihydrofolate reductase initiation zone.
Lubelsky Y, Sasaki T, Kuipers MA, Lucas I, Le Beau MM, Carignon S, Debatisse M, Prinz JA, Dennis JH, Gilbert DM. Lubelsky Y, et al. Nucleic Acids Res. 2011 Apr;39(8):3141-55. doi: 10.1093/nar/gkq1276. Epub 2010 Dec 9. Nucleic Acids Res. 2011. PMID: 21148149 Free PMC article.
Highly stable loading of Mcm proteins onto chromatin in living cells requires replication to unload.
Kuipers MA, Stasevich TJ, Sasaki T, Wilson KA, Hazelwood KL, McNally JG, Davidson MW, Gilbert DM. Kuipers MA, et al. J Cell Biol. 2011 Jan 10;192(1):29-41. doi: 10.1083/jcb.201007111. J Cell Biol. 2011. PMID: 21220507 Free PMC article.
Replication timing: a fingerprint for cell identity and pluripotency.
Ryba T, Hiratani I, Sasaki T, Battaglia D, Kulik M, Zhang J, Dalton S, Gilbert DM. Ryba T, et al. PLoS Comput Biol. 2011 Oct;7(10):e1002225. doi: 10.1371/journal.pcbi.1002225. Epub 2011 Oct 20. PLoS Comput Biol. 2011. PMID: 22028635 Free PMC article.
Murine esBAF chromatin remodeling complex subunits BAF250a and Brg1 are necessary to maintain and reprogram pluripotency-specific replication timing of select replication domains.
Takebayashi S, Lei I, Ryba T, Sasaki T, Dileep V, Battaglia D, Gao X, Fang P, Fan Y, Esteban MA, Tang J, Crabtree GR, Wang Z, Gilbert DM. Takebayashi S, et al. Epigenetics Chromatin. 2013 Dec 13;6(1):42. doi: 10.1186/1756-8935-6-42. Epigenetics Chromatin. 2013. PMID: 24330833 Free PMC article.
The distribution of genomic variations in human iPSCs is related to replication-timing reorganization during reprogramming.
Lu J, Li H, Hu M, Sasaki T, Baccei A, Gilbert DM, Liu JS, Collins JJ, Lerou PH. Lu J, et al. Cell Rep. 2014 Apr 10;7(1):70-8. doi: 10.1016/j.celrep.2014.03.007. Epub 2014 Mar 27. Cell Rep. 2014. PMID: 24685138 Free PMC article.
Unearthing worm replication origins.
Sasaki T, Gilbert DM. Sasaki T, et al. Nat Struct Mol Biol. 2017 Mar 3;24(3):195-196. doi: 10.1038/nsmb.3385. Nat Struct Mol Biol. 2017. PMID: 28257138 No abstract available.
Stability of patient-specific features of altered DNA replication timing in xenografts of primary human acute lymphoblastic leukemia.
Sasaki T, Rivera-Mulia JC, Vera D, Zimmerman J, Das S, Padget M, Nakamichi N, Chang BH, Tyner J, Druker BJ, Weng AP, Civin CI, Eaves CJ, Gilbert DM. Sasaki T, et al. Exp Hematol. 2017 Jul;51:71-82.e3. doi: 10.1016/j.exphem.2017.04.004. Epub 2017 Apr 19. Exp Hematol. 2017. PMID: 28433605 Free PMC article.
To examine the stability of DNA RT profiles of serially passaged xenografts of primary human B- and T-ALL cells, we first devised a method that circumvents the need for bromodeoxyuridine incorporation to distinguish early versus late S-phase cells. ...
To examine the stability of DNA RT profiles of serially passaged xenografts of primary human B- and T-ALL cells, we first devised a m …
Genome-wide analysis of replication timing by next-generation sequencing with E/L Repli-seq.
Marchal C, Sasaki T, Vera D, Wilson K, Sima J, Rivera-Mulia JC, Trevilla-García C, Nogues C, Nafie E, Gilbert DM. Marchal C, et al. Nat Protoc. 2018 May;13(5):819-839. doi: 10.1038/nprot.2017.148. Epub 2018 Mar 29. Nat Protoc. 2018. PMID: 29599440 Free PMC article.
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