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Roles of heparan-sulphate glycosaminoglycans in cancer.
Sasisekharan R, Shriver Z, Venkataraman G, Narayanasami U. Sasisekharan R, et al. Nat Rev Cancer. 2002 Jul;2(7):521-8. doi: 10.1038/nrc842. Nat Rev Cancer. 2002. PMID: 12094238 Review. No abstract available.
Glycan topology determines human adaptation of avian H5N1 virus hemagglutinin.
Chandrasekaran A, Srinivasan A, Raman R, Viswanathan K, Raguram S, Tumpey TM, Sasisekharan V, Sasisekharan R. Chandrasekaran A, et al. Among authors: sasisekharan v, sasisekharan r. Nat Biotechnol. 2008 Jan;26(1):107-13. doi: 10.1038/nbt1375. Epub 2008 Jan 6. Nat Biotechnol. 2008. PMID: 18176555
The soft palate is an important site of adaptation for transmissible influenza viruses.
Lakdawala SS, Jayaraman A, Halpin RA, Lamirande EW, Shih AR, Stockwell TB, Lin X, Simenauer A, Hanson CT, Vogel L, Paskel M, Minai M, Moore I, Orandle M, Das SR, Wentworth DE, Sasisekharan R, Subbarao K. Lakdawala SS, et al. Among authors: sasisekharan r. Nature. 2015 Oct 1;526(7571):122-5. doi: 10.1038/nature15379. Epub 2015 Sep 23. Nature. 2015. PMID: 26416728 Free PMC article.
The heparin/heparan sulfate 2-O-sulfatase from Flavobacterium heparinum. Molecular cloning, recombinant expression, and biochemical characterization.
Myette JR, Shriver Z, Claycamp C, McLean MW, Venkataraman G, Sasisekharan R. Myette JR, et al. Among authors: sasisekharan r. J Biol Chem. 2003 Apr 4;278(14):12157-66. doi: 10.1074/jbc.M211420200. Epub 2003 Jan 7. J Biol Chem. 2003. PMID: 12519775
We recently reported of one such enzyme, the Delta4,5-glycuronidase cloned from Flavobacterium heparinum and recombinantly expressed in Escherichia coli (Myette, J. R., Shriver, Z., Kiziltepe, T., McLean, M. W., Venkataraman, G., and Sasisekharan, R. (2002) B …
We recently reported of one such enzyme, the Delta4,5-glycuronidase cloned from Flavobacterium heparinum and recombinantly expressed in Esch …
Exploiting nanotechnology to target cancer.
Sengupta S, Sasisekharan R. Sengupta S, et al. Among authors: sasisekharan r. Br J Cancer. 2007 May 7;96(9):1315-9. doi: 10.1038/sj.bjc.6603707. Epub 2007 Apr 3. Br J Cancer. 2007. PMID: 17406364 Free PMC article. Review.
Glycome and transcriptome regulation of vasculogenesis.
Harfouche R, Hentschel DM, Piecewicz S, Basu S, Print C, Eavarone D, Kiziltepe T, Sasisekharan R, Sengupta S. Harfouche R, et al. Among authors: sasisekharan r. Circulation. 2009 Nov 10;120(19):1883-1892. doi: 10.1161/CIRCULATIONAHA.108.837724. Epub 2009 Oct 26. Circulation. 2009. PMID: 19858418 Free PMC article.
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