Sattler M - Search Results

1

Celastrol-Induced Weight Loss Is Driven by Hypophagia and Independent From UCP1.

Pfuhlmann K, Schriever SC, Baumann P, Kabra DG, Harrison L, Mazibuko-Mbeje SE, Contreras RE, Kyriakou E, Simonds SE, Tiganis T, Cowley MA, Woods SC, Jastroch M, Clemmensen C, De Angelis M, Schramm KW, Sattler M, Messias AC, Tschöp MH, Pfluger PT. Pfuhlmann K, et al. Among authors: sattler m. Diabetes. 2018 Nov;67(11):2456-2465. doi: 10.2337/db18-0146. Epub 2018 Aug 28. Diabetes. 2018. PMID: 30158241

2

Structural basis of single-stranded RNA recognition.

Messias AC, Sattler M. Messias AC, et al. Among authors: sattler m. Acc Chem Res. 2004 May;37(5):279-87. doi: 10.1021/ar030034m. Acc Chem Res. 2004. PMID: 15147168 Review.

3

X-ray crystallographic and NMR studies of the third KH domain of hnRNP K in complex with single-stranded nucleic acids.

Backe PH, Messias AC, Ravelli RB, Sattler M, Cusack S. Backe PH, et al. Among authors: sattler m. Structure. 2005 Jul;13(7):1055-67. doi: 10.1016/j.str.2005.04.008. Structure. 2005. PMID: 16004877 Free article.

4

The DICE-binding activity of KH domain 3 of hnRNP K is affected by c-Src-mediated tyrosine phosphorylation.

Messias AC, Harnisch C, Ostareck-Lederer A, Sattler M, Ostareck DH. Messias AC, et al. Among authors: sattler m. J Mol Biol. 2006 Aug 18;361(3):470-81. doi: 10.1016/j.jmb.2006.06.025. Epub 2006 Jun 30. J Mol Biol. 2006. PMID: 16854432

5

Structural Characterization of LRRK2 Inhibitors.

Gilsbach BK, Messias AC, Ito G, Sattler M, Alessi DR, Wittinghofer A, Kortholt A. Gilsbach BK, et al. Among authors: sattler m. J Med Chem. 2015 May 14;58(9):3751-6. doi: 10.1021/jm5018779. Epub 2015 May 1. J Med Chem. 2015. PMID: 25897865

6

Inhibition of Canonical NF-κB Signaling by a Small Molecule Targeting NEMO-Ubiquitin Interaction.

Vincendeau M, Hadian K, Messias AC, Brenke JK, Halander J, Griesbach R, Greczmiel U, Bertossi A, Stehle R, Nagel D, Demski K, Velvarska H, Niessing D, Geerlof A, Sattler M, Krappmann D. Vincendeau M, et al. Among authors: sattler m. Sci Rep. 2016 Jan 7;6:18934. doi: 10.1038/srep18934. Sci Rep. 2016. PMID: 26740240 Free PMC article.

7

Pitchfork and Gprasp2 Target Smoothened to the Primary Cilium for Hedgehog Pathway Activation.

Jung B, Padula D, Burtscher I, Landerer C, Lutter D, Theis F, Messias AC, Geerlof A, Sattler M, Kremmer E, Boldt K, Ueffing M, Lickert H. Jung B, et al. Among authors: sattler m. PLoS One. 2016 Feb 22;11(2):e0149477. doi: 10.1371/journal.pone.0149477. eCollection 2016. PLoS One. 2016. PMID: 26901434 Free PMC article.

8

Novel small molecules targeting ciliary transport of Smoothened and oncogenic Hedgehog pathway activation.

Jung B, Messias AC, Schorpp K, Geerlof A, Schneider G, Saur D, Hadian K, Sattler M, Wanker EE, Hasenöder S, Lickert H. Jung B, et al. Among authors: sattler m. Sci Rep. 2016 Mar 2;6:22540. doi: 10.1038/srep22540. Sci Rep. 2016. PMID: 26931153 Free PMC article.

9

The Structure of the SPOP-Pdx1 Interface Reveals Insights into the Phosphorylation-Dependent Binding Regulation.

Ostertag MS, Messias AC, Sattler M, Popowicz GM. Ostertag MS, et al. Among authors: sattler m. Structure. 2019 Feb 5;27(2):327-334.e3. doi: 10.1016/j.str.2018.10.005. Epub 2018 Nov 15. Structure. 2019. PMID: 30449689 Free article.

10

Celastrol Promotes Weight Loss in Diet-Induced Obesity by Inhibiting the Protein Tyrosine Phosphatases PTP1B and TCPTP in the Hypothalamus.

Kyriakou E, Schmidt S, Dodd GT, Pfuhlmann K, Simonds SE, Lenhart D, Geerlof A, Schriever SC, De Angelis M, Schramm KW, Plettenburg O, Cowley MA, Tiganis T, Tschöp MH, Pfluger PT, Sattler M, Messias AC. Kyriakou E, et al. Among authors: sattler m. J Med Chem. 2018 Dec 27;61(24):11144-11157. doi: 10.1021/acs.jmedchem.8b01224. Epub 2018 Dec 7. J Med Chem. 2018. PMID: 30525586

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