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Reduction in alkaline phosphatase is associated with longer survival in primary sclerosing cholangitis, independent of dominant stenosis
Rupp C, et al. Aliment Pharmacol Ther 2014. Among authors: Sauer P. PMID 25316001
Achievement of each score was associated with longer transplantation-free survival in all three groups (ALP reduction 1: no DS P = 0.001; DS early P < 0.001; DS late P = 0.022; ALP reduction 2: no DS P = 0.014; DS early P = 0.001; DS late P = 0.002). ...We further analysed previously published scores of ALP improvement in PSC showing also improved survival in patients with ALP normalisation or a reduction below 1.5 times of ULN (P = 0.003, P = 0.001, respectively), whereas the score determined by 40% reduction did not show significant differences in survival (P = 0.55). ...
Achievement of each score was associated with longer transplantation-free survival in all three groups (ALP reduction 1: no DS P = 0. …
Efficacy of ursodeoxycholic acid treatment and endoscopic dilation of major duct stenoses in primary sclerosing cholangitis. An 8-year prospective study
Stiehl A, et al. J Hepatol 1997 - Clinical Trial. Among authors: Sauer P. PMID 9075663
The actuarial Kaplan-Meier survival probabilities without liver transplantation after treatment with ursodeoxycholic acid and dilation of major duct stenoses were significantly improved compared to the predicted survival rates with p=0.001. ...
The actuarial Kaplan-Meier survival probabilities without liver transplantation after treatment with ursodeoxycholic acid and dilation of ma …
Primary sclerosing cholangitis
Stiehl A, et al. Can J Gastroenterol 2000 - Review. Among authors: Sauer P. PMID 10799084
[Therapy of primary sclerosing cholangitis]
Stiehl A, et al. Praxis (Bern 1994) 2000. Among authors: Sauer P. PMID 10893998 German.
Development of dominant bile duct stenoses in patients with primary sclerosing cholangitis treated with ursodeoxycholic acid: outcome after endoscopic treatment
Stiehl A, et al. J Hepatol 2002 - Clinical Trial. Among authors: Sauer P. PMID 11830325
The actuarial survival free of liver transplantation of the whole group at 3, 5 and 7 years were 0.987, 0.935 and 0.891 and the corresponding survival rates predicted with the Mayo multicenter survival model were 0.860, 0.775 and 0.737 (P<0.001). ...
The actuarial survival free of liver transplantation of the whole group at 3, 5 and 7 years were 0.987, 0.935 and 0.891 and the correspondin …
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