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Neonatal varicella.
Sauerbrei A, Wutzler P. Sauerbrei A, et al. J Perinatol. 2001 Dec;21(8):545-9. doi: 10.1038/sj.jp.7210599. J Perinatol. 2001. PMID: 11774017 Review.
A fatal outcome has been reported in 23% of cases if neonatal chickenpox occurs between 5 and 10 to 12 days of age. Serological methods have been widely used to confirm clinical diagnosis. ...
A fatal outcome has been reported in 23% of cases if neonatal chickenpox occurs between 5 and 10 to 12 days of age. Serological metho
[Varicella zoster virus infections in pregnancy].
Sauerbrei A, Wutzler P. Sauerbrei A, et al. Zentralbl Gynakol. 1992;114(5):259-64. Zentralbl Gynakol. 1992. PMID: 1320803 German.
Varicella in pregnancy are a rare event, but they may result in severe disease of child. During the first and second trimenon they may cause congenital defects, so-called congenital varicella syndrome. Primary infections with the varicella-zoster virus are also a ri …
Varicella in pregnancy are a rare event, but they may result in severe disease of child. During the first and second trimenon they ma …
Drug resistance of clinical varicella-zoster virus strains confirmed by recombinant thymidine kinase expression and by targeted resistance mutagenesis of a cloned wild-type isolate.
Brunnemann AK, Bohn-Wippert K, Zell R, Henke A, Walther M, Braum O, Maschkowitz G, Fickenscher H, Sauerbrei A, Krumbholz A. Brunnemann AK, et al. Among authors: sauerbrei a. Antimicrob Agents Chemother. 2015 May;59(5):2726-34. doi: 10.1128/AAC.05115-14. Epub 2015 Feb 23. Antimicrob Agents Chemother. 2015. PMID: 25712361 Free PMC article.
Initially, recombinant TK proteins containing amino acid substitutions described as known or suspected causes of antiviral resistance were analyzed by measuring the TK activity by applying a modified commercial enzyme immunoassay. ...In conclusion, analyzing the enzymatic …
Initially, recombinant TK proteins containing amino acid substitutions described as known or suspected causes of antiviral resistance were a …
Laboratory diagnosis of herpes zoster.
Sauerbrei A, Eichhorn U, Schacke M, Wutzler P. Sauerbrei A, et al. J Clin Virol. 1999 Sep;14(1):31-6. doi: 10.1016/s1386-6532(99)00042-6. J Clin Virol. 1999. PMID: 10548128 Clinical Trial.
The sensitivity of virus culture was 20% (specificity 100%), of direct immunofluorescent VZV-specific antigen staining in vesicle samples 82% (specificity 76%), and in 48% there was a serological response to specific IgM and IgA antibodies within 4 days after the onset of …
The sensitivity of virus culture was 20% (specificity 100%), of direct immunofluorescent VZV-specific antigen staining in vesicle samples 82 …
Fatal varicella in an immunocompromised adult associated with a European genotype E2 variant of varicella zoster virus.
Springfeld C, Sauerbrei A, Filusch A, Konstandin M, Hartschuh W, Sauer P, Encke J, Stremmel W, Schnitzler P. Springfeld C, et al. Among authors: sauerbrei a. J Clin Virol. 2009 Jan;44(1):70-3. doi: 10.1016/j.jcv.2008.10.004. Epub 2008 Dec 3. J Clin Virol. 2009. PMID: 19056312
A 25-year-old male patient presented with rash and hepatitis. He had been known to suffer from Crohn's disease and received immunosuppressive treatment with azathioprine. The patient showed dyspnoea, and presented with a generalized rash with vesicular lesions typic
A 25-year-old male patient presented with rash and hepatitis. He had been known to suffer from Crohn's disease and received immunosup
Variability of immediate-early gene 62 in german varicella-zoster virus wild-type strains.
Sauerbrei A, Bohn K, Zell R, Wutzler P. Sauerbrei A, et al. J Clin Microbiol. 2009 Nov;47(11):3717-20. doi: 10.1128/JCM.01550-09. Epub 2009 Aug 26. J Clin Microbiol. 2009. PMID: 19710264 Free PMC article.
Varicella-zoster virus strains of European genotypes have developed a high variability of open reading frame (ORF) 62 during their occurrence over many years in Germany. M1 strains in Germany display a uniform ORF 62 pattern, suggesting that these strains were intro …
Varicella-zoster virus strains of European genotypes have developed a high variability of open reading frame (ORF) 62 during their oc …
Multiple viral infections after haploidentical hematopoietic stem cell transplantation in a child with acute lymphoblastic leukemia.
Ernst J, Sauerbrei A, Krumbholz A, Egerer R, Mentzel HJ, Kurzai M, Häfer R, Beck JF, Gruhn B. Ernst J, et al. Among authors: sauerbrei a. Transpl Infect Dis. 2012 Oct;14(5):E82-8. doi: 10.1111/j.1399-3062.2012.00778.x. Epub 2012 Aug 3. Transpl Infect Dis. 2012. PMID: 22862952
After allogeneic hematopoietic stem cell transplantation (HSCT), viral infections/reactivations are a frequent complication, sometimes with fatal outcome. ...Herein, we present the case of a child with Philadelphia chromosome-positive acute lymphoblastic leukemia af …
After allogeneic hematopoietic stem cell transplantation (HSCT), viral infections/reactivations are a frequent complication, sometime …
Herpes simplex and varicella-zoster virus infections during pregnancy: current concepts of prevention, diagnosis and therapy. Part 1: herpes simplex virus infections.
Sauerbrei A, Wutzler P. Sauerbrei A, et al. Med Microbiol Immunol. 2007 Jun;196(2):89-94. doi: 10.1007/s00430-006-0031-0. Epub 2006 Dec 13. Med Microbiol Immunol. 2007. PMID: 17165093 Review.
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