Sauve AA - Search Results

1

PARP-1 inhibition increases mitochondrial metabolism through SIRT1 activation.

Bai P, Cantó C, Oudart H, Brunyánszki A, Cen Y, Thomas C, Yamamoto H, Huber A, Kiss B, Houtkooper RH, Schoonjans K, Schreiber V, Sauve AA, Menissier-de Murcia J, Auwerx J. Bai P, et al. Among authors: sauve aa. Cell Metab. 2011 Apr 6;13(4):461-468. doi: 10.1016/j.cmet.2011.03.004. Cell Metab. 2011. PMID: 21459330 Free PMC article.

2

SIRT1 and endocrine signaling.

Yang T, Fu M, Pestell R, Sauve AA. Yang T, et al. Among authors: sauve aa. Trends Endocrinol Metab. 2006 Jul;17(5):186-91. doi: 10.1016/j.tem.2006.04.002. Epub 2006 May 8. Trends Endocrinol Metab. 2006. PMID: 16684606 Review.

3

Glucose restriction inhibits skeletal myoblast differentiation by activating SIRT1 through AMPK-mediated regulation of Nampt.

Fulco M, Cen Y, Zhao P, Hoffman EP, McBurney MW, Sauve AA, Sartorelli V. Fulco M, et al. Among authors: sauve aa. Dev Cell. 2008 May;14(5):661-73. doi: 10.1016/j.devcel.2008.02.004. Dev Cell. 2008. PMID: 18477450 Free PMC article.

4

Plasmodium falciparum Sir2 is an NAD+-dependent deacetylase and an acetyllysine-dependent and acetyllysine-independent NAD+ glycohydrolase.

French JB, Cen Y, Sauve AA. French JB, et al. Among authors: sauve aa. Biochemistry. 2008 Sep 23;47(38):10227-39. doi: 10.1021/bi800767t. Epub 2008 Aug 26. Biochemistry. 2008. PMID: 18729382 Free PMC article.

5

Global analysis of transcriptional regulation by poly(ADP-ribose) polymerase-1 and poly(ADP-ribose) glycohydrolase in MCF-7 human breast cancer cells.

Frizzell KM, Gamble MJ, Berrocal JG, Zhang T, Krishnakumar R, Cen Y, Sauve AA, Kraus WL. Frizzell KM, et al. Among authors: sauve aa. J Biol Chem. 2009 Dec 4;284(49):33926-38. doi: 10.1074/jbc.M109.023879. Epub 2009 Oct 7. J Biol Chem. 2009. PMID: 19812418 Free PMC article.

6

Diastereocontrolled electrophilic fluorinations of 2-deoxyribonolactone: syntheses of all corresponding 2-deoxy-2-fluorolactones and 2'-deoxy-2'-fluoro-NAD+s.

Cen Y, Sauve AA. Cen Y, et al. Among authors: sauve aa. J Org Chem. 2009 Aug 21;74(16):5779-89. doi: 10.1021/jo900637f. J Org Chem. 2009. PMID: 19958035 Free PMC article.

7

Efficient syntheses of clofarabine and gemcitabine from 2-deoxyribonolactone.

Cen Y, Sauve AA. Cen Y, et al. Among authors: sauve aa. Nucleosides Nucleotides Nucleic Acids. 2010 Feb;29(2):113-22. doi: 10.1080/15257771003597758. Nucleosides Nucleotides Nucleic Acids. 2010. PMID: 20391198

8

Transition state of ADP-ribosylation of acetyllysine catalyzed by Archaeoglobus fulgidus Sir2 determined by kinetic isotope effects and computational approaches.

Cen Y, Sauve AA. Cen Y, et al. Among authors: sauve aa. J Am Chem Soc. 2010 Sep 8;132(35):12286-98. doi: 10.1021/ja910342d. J Am Chem Soc. 2010. PMID: 20718419 Free PMC article.

9

High-resolution crystal structures of Streptococcus pneumoniae nicotinamidase with trapped intermediates provide insights into the catalytic mechanism and inhibition by aldehydes.

French JB, Cen Y, Sauve AA, Ealick SE. French JB, et al. Among authors: sauve aa. Biochemistry. 2010 Oct 12;49(40):8803-12. doi: 10.1021/bi1012436. Epub 2010 Sep 20. Biochemistry. 2010. PMID: 20853856 Free PMC article.

10

Identification of the aryl hydrocarbon receptor target gene TiPARP as a mediator of suppression of hepatic gluconeogenesis by 2,3,7,8-tetrachlorodibenzo-p-dioxin and of nicotinamide as a corrective agent for this effect.

Diani-Moore S, Ram P, Li X, Mondal P, Youn DY, Sauve AA, Rifkind AB. Diani-Moore S, et al. Among authors: sauve aa. J Biol Chem. 2010 Dec 10;285(50):38801-10. doi: 10.1074/jbc.M110.131573. Epub 2010 Sep 28. J Biol Chem. 2010. PMID: 20876576 Free PMC article.

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