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NF-κB is a critical mediator of BRCA1-induced chemoresistance.
Harte MT, Gorski JJ, Savage KI, Purcell JW, Barros EM, Burn PM, McFarlane C, Mullan PB, Kennedy RD, Perkins ND, Harkin DP. Harte MT, et al. Among authors: savage ki. Oncogene. 2014 Feb 6;33(6):713-723. doi: 10.1038/onc.2013.10. Epub 2013 Feb 25. Oncogene. 2014. PMID: 23435429 Free PMC article.
BRCA1 deficiency exacerbates estrogen-induced DNA damage and genomic instability.
Savage KI, Matchett KB, Barros EM, Cooper KM, Irwin GW, Gorski JJ, Orr KS, Vohhodina J, Kavanagh JN, Madden AF, Powell A, Manti L, McDade SS, Park BH, Prise KM, McIntosh SA, Salto-Tellez M, Richard DJ, Elliott CT, Harkin DP. Savage KI, et al. Cancer Res. 2014 May 15;74(10):2773-2784. doi: 10.1158/0008-5472.CAN-13-2611. Epub 2014 Mar 17. Cancer Res. 2014. PMID: 24638981 Free PMC article.
Identification of a BRCA1-mRNA splicing complex required for efficient DNA repair and maintenance of genomic stability.
Savage KI, Gorski JJ, Barros EM, Irwin GW, Manti L, Powell AJ, Pellagatti A, Lukashchuk N, McCance DJ, McCluggage WG, Schettino G, Salto-Tellez M, Boultwood J, Richard DJ, McDade SS, Harkin DP. Savage KI, et al. Mol Cell. 2014 May 8;54(3):445-59. doi: 10.1016/j.molcel.2014.03.021. Epub 2014 Apr 17. Mol Cell. 2014. PMID: 24746700 Free PMC article.
Activation of STING-Dependent Innate Immune Signaling By S-Phase-Specific DNA Damage in Breast Cancer.
Parkes EE, Walker SM, Taggart LE, McCabe N, Knight LA, Wilkinson R, McCloskey KD, Buckley NE, Savage KI, Salto-Tellez M, McQuaid S, Harte MT, Mullan PB, Harkin DP, Kennedy RD. Parkes EE, et al. Among authors: savage ki. J Natl Cancer Inst. 2016 Oct 5;109(1):djw199. doi: 10.1093/jnci/djw199. Print 2017 Jan. J Natl Cancer Inst. 2016. PMID: 27707838 Free PMC article.
42 results