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Prehospital transdermal glyceryl trinitrate for ultra-acute ischaemic stroke: data from the RIGHT-2 randomised sham-controlled ambulance trial.
Appleton JP, Woodhouse LJ, Anderson CS, Ankolekar S, Cala L, Dixon M, England TJ, Krishnan K, Mair G, Muir KW, Potter J, Price CI, Randall M, Robinson TG, Roffe C, Sandset EC, Saver JL, Shone A, Siriwardena AN, Wardlaw JM, Sprigg N, Bath PM; RIGHT-2 Investigators. Appleton JP, et al. Stroke Vasc Neurol. 2024 Feb 27;9(1):38-49. doi: 10.1136/svn-2022-001634. Stroke Vasc Neurol. 2024. PMID: 37290930 Free PMC article. Clinical Trial.
Secondary outcomes included death; a global analysis (Wei-Lachin test) containing Barthel Index, EuroQol-5D, mRS, telephone interview for cognitive status-modified and Zung depression scale; and neuroimaging-determined 'brain frailty' markers. ...
Secondary outcomes included death; a global analysis (Wei-Lachin test) containing Barthel Index, EuroQol-5D, mRS, telephone interview …
A Prospective Multicenter Analysis of Mobile Stroke Unit Cost-Effectiveness.
Rajan SS, Yamal JM, Wang M, Saver JL, Jacob AP, Gonzales NR, Ifejika N, Parker SA, Ganey C, Gonzalez MO, Lairson DR, Bratina PL, Jones WJ, Mackey JS, Lerario MP, Navi BB, Alexandrov AW, Alexandrov A, Nour M, Spokoyny I, Bowry R, Czap AL, Grotta JC. Rajan SS, et al. Ann Neurol. 2025 Feb;97(2):209-221. doi: 10.1002/ana.27105. Epub 2024 Dec 3. Ann Neurol. 2025. PMID: 39625067 Clinical Trial.
Quality-adjusted life years (QALYs) estimated using patient-reported EQ-5D-5L data were used as the effectiveness measure. Health care utilizations were converted to costs using average national Medicare reimbursements. ...
Quality-adjusted life years (QALYs) estimated using patient-reported EQ-5D-5L data were used as the effectiveness measure. Health car …
Incremental benefits of circumferential minimally invasive surgery for increasingly frail patients with adult spinal deformity.
Passias PG, Tretiakov PS, Nunley PD, Wang MY, Park P, Kanter AS, Okonkwo DO, Eastlack RK, Mundis GM, Chou D, Agarwal N, Fessler RG, Uribe JS, Anand N, Than KD, Brusko G, Fu KM, Turner JD, Le VP, Line BG, Ames CP, Smith JS, Shaffrey CI, Hart RA, Burton D, Lafage R, Lafage V, Schwab F, Bess S, Mummaneni PV. Passias PG, et al. J Neurosurg Spine. 2023 Apr 21;39(2):168-174. doi: 10.3171/2023.2.SPINE221278. Print 2023 Aug 1. J Neurosurg Spine. 2023. PMID: 37086158

Perioperatively, cMIS patients had lower intraoperative blood loss and decreased use of cell saver across frailty groups (with adjustment for baseline age, CCI score, and levels fused), as well as fewer perioperative complications (p < 0.001). Adjusted analysis also rev

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Perioperatively, cMIS patients had lower intraoperative blood loss and decreased use of cell saver across frailty groups (with adjust …
Improving economic evaluations in stroke: A report from the ESO Health Economics Working Group.
Cadilhac DA, Kim J, Wilson A, Berge E, Patel A, Ali M, Saver J, Christensen H, Cuche M, Crews S, Wu O, Provoyeur M, McMeekin P, Durand-Zaleski I, Ford GA, Muhlemann N, Bath PM, Abdul-Rahim AH, Sunnerhagen K, Meretoja A, Thijs V, Weimar C, Massaro A, Ranta A, Lees KR; ESO Health Economics Working group. Cadilhac DA, et al. Eur Stroke J. 2020 Jun;5(2):184-192. doi: 10.1177/2396987319897466. Epub 2020 Jan 27. Eur Stroke J. 2020. PMID: 32637652 Free PMC article.
Preferred functional/quality of life outcome measures to use for economic evaluations were the modified Rankin Scale (14 respondents, 88%) and the EQ-5D instrument (11 respondents, 69%). Of the 12 respondents who had access to data used in economic evaluations, 10 (83%) in …
Preferred functional/quality of life outcome measures to use for economic evaluations were the modified Rankin Scale (14 respondents, 88%) a …