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Long term management of patients with cryopyrin-associated periodic syndromes (CAPS): focus on rilonacept (IL-1 Trap).
Church LD, Savic S, McDermott MF. Church LD, et al. Among authors: savic s. Biologics. 2008 Dec;2(4):733-42. doi: 10.2147/btt.s3167. Biologics. 2008. PMID: 19707454 Free PMC article.
Familial Mediterranean fever and related periodic fever syndromes/autoinflammatory diseases.
Savic S, Dickie LJ, Battellino M, McDermott MF. Savic S, et al. Curr Opin Rheumatol. 2012 Jan;24(1):103-12. doi: 10.1097/BOR.0b013e32834dd2d5. Curr Opin Rheumatol. 2012. PMID: 22089100 Review.
Late-Onset Cryopyrin-Associated Periodic Syndromes Caused by Somatic NLRP3 Mosaicism-UK Single Center Experience.
Rowczenio DM, Gomes SM, Aróstegui JI, Mensa-Vilaro A, Omoyinmi E, Trojer H, Baginska A, Baroja-Mazo A, Pelegrin P, Savic S, Lane T, Williams R, Brogan P, Lachmann HJ, Hawkins PN. Rowczenio DM, et al. Among authors: savic s. Front Immunol. 2017 Oct 31;8:1410. doi: 10.3389/fimmu.2017.01410. eCollection 2017. Front Immunol. 2017. PMID: 29163488 Free PMC article.
Moving towards a systems-based classification of innate immune-mediated diseases.
Savic S, Caseley EA, McDermott MF. Savic S, et al. Nat Rev Rheumatol. 2020 Apr;16(4):222-237. doi: 10.1038/s41584-020-0377-5. Epub 2020 Feb 27. Nat Rev Rheumatol. 2020. PMID: 32107482 Review.
Different CFTR modulator combinations downregulate inflammation differently in cystic fibrosis.
Jarosz-Griffiths HH, Scambler T, Wong CH, Lara-Reyna S, Holbrook J, Martinon F, Savic S, Whitaker P, Etherington C, Spoletini G, Clifton I, Mehta A, McDermott MF, Peckham D. Jarosz-Griffiths HH, et al. Among authors: savic s. Elife. 2020 Mar 2;9:e54556. doi: 10.7554/eLife.54556. Elife. 2020. PMID: 32118580 Free PMC article.
COVID-19 meets Cystic Fibrosis: for better or worse?
Peckham D, McDermott MF, Savic S, Mehta A. Peckham D, et al. Among authors: savic s. Genes Immun. 2020 Aug;21(4):260-262. doi: 10.1038/s41435-020-0103-y. Epub 2020 Jul 1. Genes Immun. 2020. PMID: 32606316 Review.
Periodic fever syndrome and autoinflammatory diseases.
Dickie LJ, Savic S, Aziz A, Sprakes M, McDermott MF. Dickie LJ, et al. Among authors: savic s. F1000 Med Rep. 2010 Jan 18;2:3. doi: 10.3410/M2-3. F1000 Med Rep. 2010. PMID: 20948856 Free PMC article.
Involvement of X-box binding protein 1 and reactive oxygen species pathways in the pathogenesis of tumour necrosis factor receptor-associated periodic syndrome.
Dickie LJ, Aziz AM, Savic S, Lucherini OM, Cantarini L, Geiler J, Wong CH, Coughlan R, Lane T, Lachmann HJ, Hawkins PN, Robinson PA, Emery P, McGonagle D, McDermott MF. Dickie LJ, et al. Among authors: savic s. Ann Rheum Dis. 2012 Dec;71(12):2035-43. doi: 10.1136/annrheumdis-2011-201197. Epub 2012 Jun 7. Ann Rheum Dis. 2012. PMID: 22679299
Anakinra as a diagnostic challenge and treatment option for systemic autoinflammatory disorders of undefined etiology.
Harrison SR, McGonagle D, Nizam S, Jarrett S, van der Hilst J, McDermott MF, Savic S. Harrison SR, et al. Among authors: savic s. JCI Insight. 2016 May 5;1(6):e86336. doi: 10.1172/jci.insight.86336. JCI Insight. 2016. PMID: 27699261 Free PMC article.
METHODS: We performed a retrospective analysis of consecutive patients presenting with uSAID between 2012-2015 who were treated with the recombinant IL-1 receptor antagonist anakinra. uSAID was diagnosed after excluding malignancy, infection, and pathogenic mutations in known her …
METHODS: We performed a retrospective analysis of consecutive patients presenting with uSAID between 2012-2015 who were treated with the rec …
Interleukin-1 Blockade: An Update on Emerging Indications.
Mistry A, Savic S, van der Hilst JCH. Mistry A, et al. Among authors: savic s. BioDrugs. 2017 Jun;31(3):207-221. doi: 10.1007/s40259-017-0224-7. BioDrugs. 2017. PMID: 28497222 Review.
In autoinflammatory diseases, gout, Schnitzler's syndrome, and adult-onset Still's disease, high levels of inappropriate IL-1 production have been shown to be a key process in the etiology of the disease. ...
In autoinflammatory diseases, gout, Schnitzler's syndrome, and adult-onset Still's disease, high levels of inappropriate IL-1 …
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