Savill J - Search Results

1

Selective ablation of alphav integrins in the central nervous system leads to cerebral hemorrhage, seizures, axonal degeneration and premature death.

McCarty JH, Lacy-Hulbert A, Charest A, Bronson RT, Crowley D, Housman D, Savill J, Roes J, Hynes RO. McCarty JH, et al. Among authors: savill j. Development. 2005 Jan;132(1):165-76. doi: 10.1242/dev.01551. Epub 2004 Dec 2. Development. 2005. PMID: 15576410

2

Ulcerative colitis and autoimmunity induced by loss of myeloid alphav integrins.

Lacy-Hulbert A, Smith AM, Tissire H, Barry M, Crowley D, Bronson RT, Roes JT, Savill JS, Hynes RO. Lacy-Hulbert A, et al. Proc Natl Acad Sci U S A. 2007 Oct 2;104(40):15823-8. doi: 10.1073/pnas.0707421104. Epub 2007 Sep 25. Proc Natl Acad Sci U S A. 2007. PMID: 17895374 Free PMC article.

3

αv Integrins combine with LC3 and atg5 to regulate Toll-like receptor signalling in B cells.

Acharya M, Sokolovska A, Tam JM, Conway KL, Stefani C, Raso F, Mukhopadhyay S, Feliu M, Paul E, Savill J, Hynes RO, Xavier RJ, Vyas JM, Stuart LM, Lacy-Hulbert A. Acharya M, et al. Among authors: savill j. Nat Commun. 2016 Mar 11;7:10917. doi: 10.1038/ncomms10917. Nat Commun. 2016. PMID: 26965188 Free PMC article.

4

Preferential expression of integrin αvβ8 promotes generation of regulatory T cells by mouse CD103+ dendritic cells.

Païdassi H, Acharya M, Zhang A, Mukhopadhyay S, Kwon M, Chow C, Stuart LM, Savill J, Lacy-Hulbert A. Païdassi H, et al. Among authors: savill j. Gastroenterology. 2011 Nov;141(5):1813-20. doi: 10.1053/j.gastro.2011.06.076. Epub 2011 Jul 13. Gastroenterology. 2011. PMID: 21745448 Free PMC article.

5

Apoptotic cells induce CD103 expression and immunoregulatory function in myeloid dendritic cell precursors through integrin αv and TGF-β activation.

Zhang A, Paidassi H, Lacy-Hulbert A, Savill J. Zhang A, et al. Among authors: savill j. PLoS One. 2020 Jul 15;15(7):e0232307. doi: 10.1371/journal.pone.0232307. eCollection 2020. PLoS One. 2020. PMID: 32667911 Free PMC article.

6

Apoptotic Cell-Directed Resolution of Lung Inflammation Requires Myeloid αv Integrin-Mediated Induction of Regulatory T Lymphocytes.

Zhang A, Lacy-Hulbert A, Anderton S, Haslett C, Savill J. Zhang A, et al. Among authors: savill j. Am J Pathol. 2020 Jun;190(6):1224-1235. doi: 10.1016/j.ajpath.2020.02.010. Epub 2020 Mar 19. Am J Pathol. 2020. PMID: 32201264 Free PMC article.

7

β8 Integrin Expression and Activation of TGF-β by Intestinal Dendritic Cells Are Determined by Both Tissue Microenvironment and Cell Lineage.

Boucard-Jourdin M, Kugler D, Endale Ahanda ML, This S, De Calisto J, Zhang A, Mora JR, Stuart LM, Savill J, Lacy-Hulbert A, Paidassi H. Boucard-Jourdin M, et al. Among authors: savill j. J Immunol. 2016 Sep 1;197(5):1968-78. doi: 10.4049/jimmunol.1600244. Epub 2016 Aug 1. J Immunol. 2016. PMID: 27481847 Free PMC article.

8

Apoptotic cells and innate immune stimuli combine to regulate macrophage cytokine secretion.

Lucas M, Stuart LM, Savill J, Lacy-Hulbert A. Lucas M, et al. Among authors: savill j. J Immunol. 2003 Sep 1;171(5):2610-5. doi: 10.4049/jimmunol.171.5.2610. J Immunol. 2003. PMID: 12928413

9

Inhibitory effects of apoptotic cell ingestion upon endotoxin-driven myeloid dendritic cell maturation.

Stuart LM, Lucas M, Simpson C, Lamb J, Savill J, Lacy-Hulbert A. Stuart LM, et al. Among authors: savill j. J Immunol. 2002 Feb 15;168(4):1627-35. doi: 10.4049/jimmunol.168.4.1627. J Immunol. 2002. PMID: 11823490

10

Requirements for apoptotic cell contact in regulation of macrophage responses.

Lucas M, Stuart LM, Zhang A, Hodivala-Dilke K, Febbraio M, Silverstein R, Savill J, Lacy-Hulbert A. Lucas M, et al. Among authors: savill j. J Immunol. 2006 Sep 15;177(6):4047-54. doi: 10.4049/jimmunol.177.6.4047. J Immunol. 2006. PMID: 16951368

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