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SVCT1 and SVCT2: key proteins for vitamin C uptake.
Savini I, Rossi A, Pierro C, Avigliano L, Catani MV. Savini I, et al. Amino Acids. 2008 Apr;34(3):347-55. doi: 10.1007/s00726-007-0555-7. Epub 2007 Jun 1. Amino Acids. 2008. PMID: 17541511 Review.
Ascorbic acid recycling in N-myc amplified human neuroblastoma cells.
Savini I, D'Angelo I, Annicchiarico-Petruzzelli M, Bellincampi L, Melino G, Avigliano L. Savini I, et al. Anticancer Res. 1998 Mar-Apr;18(2A):819-22. Anticancer Res. 1998. PMID: 9615725
Ascorbic acid maintenance in HaCaT cells prevents radical formation and apoptosis by UV-B.
Savini I, D'Angelo I, Ranalli M, Melino G, Avigliano L. Savini I, et al. Free Radic Biol Med. 1999 May;26(9-10):1172-80. doi: 10.1016/s0891-5849(98)00311-6. Free Radic Biol Med. 1999. PMID: 10381188
Characterization of keratinocyte differentiation induced by ascorbic acid: protein kinase C involvement and vitamin C homeostasis.
Savini I, Catani MV, Rossi A, Duranti G, Melino G, Avigliano L. Savini I, et al. J Invest Dermatol. 2002 Feb;118(2):372-9. doi: 10.1046/j.0022-202x.2001.01624.x. J Invest Dermatol. 2002. PMID: 11841559
Indeed, we found that, unlike calcium, differentiation promoted by ascorbate was accompanied by (i) an enhanced ascorbate transport, due to overexpression of specific transporters, (ii) a great efficiency of dehydroascorbate uptake, and (iii) an increase in glutathione con …
Indeed, we found that, unlike calcium, differentiation promoted by ascorbate was accompanied by (i) an enhanced ascorbate transport, …
Ascorbate up-regulates MLH1 (Mut L homologue-1) and p73: implications for the cellular response to DNA damage.
Catani MV, Costanzo A, Savini I, Levrero M, de Laurenzi V, Wang JY, Melino G, Avigliano L. Catani MV, et al. Biochem J. 2002 Jun 1;364(Pt 2):441-7. doi: 10.1042/BJ20011713. Biochem J. 2002. PMID: 12023887 Free PMC article.
We have found previously that ascorbic acid (vitamin C), as well as acting as a radical scavenger, may modulate the expression of several genes [i.e. fra-1, glutathione S-transferase Pi (GSTpi) and Mut L homologue-1 (MLH1)] in human keratinocytes. ...Our results were furth …
We have found previously that ascorbic acid (vitamin C), as well as acting as a radical scavenger, may modulate the expression of several ge …
Vitamin C recycling is enhanced in the adaptive response to leptin-induced oxidative stress in keratinocytes.
Savini I, Catani MV, Rossi A, Duranti G, Ranalli M, Melino G, Sabatini S, Avigliano L. Savini I, et al. J Invest Dermatol. 2003 Oct;121(4):786-93. doi: 10.1046/j.1523-1747.2003.12538.x. J Invest Dermatol. 2003. PMID: 14632197
We also evaluated the systems involved in the maintenance of a positive ascorbate/dehydroascorbate ratio, i.e., transport and recycling. ...
We also evaluated the systems involved in the maintenance of a positive ascorbate/dehydroascorbate ratio, i.e., transport and recycli …
Vitamin C homeostasis in skeletal muscle cells.
Savini I, Catani MV, Duranti G, Ceci R, Sabatini S, Avigliano L. Savini I, et al. Free Radic Biol Med. 2005 Apr 1;38(7):898-907. doi: 10.1016/j.freeradbiomed.2004.12.009. Free Radic Biol Med. 2005. PMID: 15749386
Biological role of vitamin C in keratinocytes.
Catani MV, Savini I, Rossi A, Melino G, Avigliano L. Catani MV, et al. Nutr Rev. 2005 Mar;63(3):81-90. doi: 10.1111/j.1753-4887.2005.tb00125.x. Nutr Rev. 2005. PMID: 15825810 Review.
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