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A Dual-Mechanism Antibiotic Kills Gram-Negative Bacteria and Avoids Drug Resistance.
Martin JK 2nd, Sheehan JP, Bratton BP, Moore GM, Mateus A, Li SH, Kim H, Rabinowitz JD, Typas A, Savitski MM, Wilson MZ, Gitai Z. Martin JK 2nd, et al. Among authors: savitski mm. Cell. 2020 Jun 25;181(7):1518-1532.e14. doi: 10.1016/j.cell.2020.05.005. Epub 2020 Jun 3. Cell. 2020. PMID: 32497502 Free PMC article.
Pervasive Protein Thermal Stability Variation during the Cell Cycle.
Becher I, Andrés-Pons A, Romanov N, Stein F, Schramm M, Baudin F, Helm D, Kurzawa N, Mateus A, Mackmull MT, Typas A, Müller CW, Bork P, Beck M, Savitski MM. Becher I, et al. Among authors: savitski mm. Cell. 2018 May 31;173(6):1495-1507.e18. doi: 10.1016/j.cell.2018.03.053. Epub 2018 Apr 26. Cell. 2018. PMID: 29706546 Free PMC article.
Species-specific activity of antibacterial drug combinations.
Brochado AR, Telzerow A, Bobonis J, Banzhaf M, Mateus A, Selkrig J, Huth E, Bassler S, Zamarreño Beas J, Zietek M, Ng N, Foerster S, Ezraty B, Py B, Barras F, Savitski MM, Bork P, Göttig S, Typas A. Brochado AR, et al. Among authors: savitski mm. Nature. 2018 Jul;559(7713):259-263. doi: 10.1038/s41586-018-0278-9. Epub 2018 Jul 4. Nature. 2018. PMID: 29973719 Free PMC article.
A new antibiotic selectively kills Gram-negative pathogens.
Imai Y, Meyer KJ, Iinishi A, Favre-Godal Q, Green R, Manuse S, Caboni M, Mori M, Niles S, Ghiglieri M, Honrao C, Ma X, Guo JJ, Makriyannis A, Linares-Otoya L, Böhringer N, Wuisan ZG, Kaur H, Wu R, Mateus A, Typas A, Savitski MM, Espinoza JL, O'Rourke A, Nelson KE, Hiller S, Noinaj N, Schäberle TF, D'Onofrio A, Lewis K. Imai Y, et al. Among authors: savitski mm. Nature. 2019 Dec;576(7787):459-464. doi: 10.1038/s41586-019-1791-1. Epub 2019 Nov 20. Nature. 2019. PMID: 31747680 Free PMC article.
The functional landscape of the human phosphoproteome.
Ochoa D, Jarnuczak AF, Viéitez C, Gehre M, Soucheray M, Mateus A, Kleefeldt AA, Hill A, Garcia-Alonso L, Stein F, Krogan NJ, Savitski MM, Swaney DL, Vizcaíno JA, Noh KM, Beltrao P. Ochoa D, et al. Among authors: savitski mm. Nat Biotechnol. 2020 Mar;38(3):365-373. doi: 10.1038/s41587-019-0344-3. Epub 2019 Dec 9. Nat Biotechnol. 2020. PMID: 31819260 Free PMC article.
Outer membrane lipoprotein NlpI scaffolds peptidoglycan hydrolases within multi-enzyme complexes in Escherichia coli.
Banzhaf M, Yau HC, Verheul J, Lodge A, Kritikos G, Mateus A, Cordier B, Hov AK, Stein F, Wartel M, Pazos M, Solovyova AS, Breukink E, van Teeffelen S, Savitski MM, den Blaauwen T, Typas A, Vollmer W. Banzhaf M, et al. Among authors: savitski mm. EMBO J. 2020 Mar 2;39(5):e102246. doi: 10.15252/embj.2019102246. Epub 2020 Feb 3. EMBO J. 2020. PMID: 32009249 Free PMC article.
Thermal proteome profiling for interrogating protein interactions.
Mateus A, Kurzawa N, Becher I, Sridharan S, Helm D, Stein F, Typas A, Savitski MM. Mateus A, et al. Among authors: savitski mm. Mol Syst Biol. 2020 Mar;16(3):e9232. doi: 10.15252/msb.20199232. Mol Syst Biol. 2020. PMID: 32133759 Free PMC article. Review.
120 results