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Regulation of immunity and oncogenesis by the IRF transcription factor family.
Savitsky D, Tamura T, Yanai H, Taniguchi T. Savitsky D, et al. Cancer Immunol Immunother. 2010 Apr;59(4):489-510. doi: 10.1007/s00262-009-0804-6. Epub 2010 Jan 5. Cancer Immunol Immunother. 2010. PMID: 20049431 Review.
Contribution of IRF5 in B cells to the development of murine SLE-like disease through its transcriptional control of the IgG2a locus.
Savitsky DA, Yanai H, Tamura T, Taniguchi T, Honda K. Savitsky DA, et al. Proc Natl Acad Sci U S A. 2010 Jun 1;107(22):10154-9. doi: 10.1073/pnas.1005599107. Epub 2010 May 17. Proc Natl Acad Sci U S A. 2010. PMID: 20479222 Free PMC article.
HMGB proteins function as universal sentinels for nucleic-acid-mediated innate immune responses.
Yanai H, Ban T, Wang Z, Choi MK, Kawamura T, Negishi H, Nakasato M, Lu Y, Hangai S, Koshiba R, Savitsky D, Ronfani L, Akira S, Bianchi ME, Honda K, Tamura T, Kodama T, Taniguchi T. Yanai H, et al. Among authors: savitsky d. Nature. 2009 Nov 5;462(7269):99-103. doi: 10.1038/nature08512. Nature. 2009. PMID: 19890330
A selective contribution of the RIG-I-like receptor pathway to type I interferon responses activated by cytosolic DNA.
Choi MK, Wang Z, Ban T, Yanai H, Lu Y, Koshiba R, Nakaima Y, Hangai S, Savitsky D, Nakasato M, Negishi H, Takeuchi O, Honda K, Akira S, Tamura T, Taniguchi T. Choi MK, et al. Among authors: savitsky d. Proc Natl Acad Sci U S A. 2009 Oct 20;106(42):17870-5. doi: 10.1073/pnas.0909545106. Epub 2009 Oct 1. Proc Natl Acad Sci U S A. 2009. PMID: 19805092 Free PMC article.
The IRF family transcription factors in immunity and oncogenesis.
Tamura T, Yanai H, Savitsky D, Taniguchi T. Tamura T, et al. Annu Rev Immunol. 2008;26:535-84. doi: 10.1146/annurev.immunol.26.021607.090400. Annu Rev Immunol. 2008. PMID: 18303999 Review.
Regulation of the cytosolic DNA-sensing system in innate immunity: a current view.
Yanai H, Savitsky D, Tamura T, Taniguchi T. Yanai H, et al. Among authors: savitsky d. Curr Opin Immunol. 2009 Feb;21(1):17-22. doi: 10.1016/j.coi.2009.01.005. Curr Opin Immunol. 2009. PMID: 19362700 Review.
Epidermal terminal differentiation depends on B lymphocyte-induced maturation protein-1.
Magnúsdóttir E, Kalachikov S, Mizukoshi K, Savitsky D, Ishida-Yamamoto A, Panteleyev AA, Calame K. Magnúsdóttir E, et al. Proc Natl Acad Sci U S A. 2007 Sep 18;104(38):14988-93. doi: 10.1073/pnas.0707323104. Epub 2007 Sep 10. Proc Natl Acad Sci U S A. 2007. PMID: 17846422 Free PMC article.
Multiple roles for Blimp-1 in B and T lymphocytes.
Savitsky D, Cimmino L, Kuo T, Martins GA, Calame K. Savitsky D, et al. Adv Exp Med Biol. 2007;596:9-30. doi: 10.1007/0-387-46530-8_2. Adv Exp Med Biol. 2007. PMID: 17338172 Review. No abstract available.
Blimp-1 is required for maintenance of long-lived plasma cells in the bone marrow.
Shapiro-Shelef M, Lin KI, Savitsky D, Liao J, Calame K. Shapiro-Shelef M, et al. J Exp Med. 2005 Dec 5;202(11):1471-6. doi: 10.1084/jem.20051611. Epub 2005 Nov 28. J Exp Med. 2005. PMID: 16314438 Free PMC article.
B-1 B lymphocytes require Blimp-1 for immunoglobulin secretion.
Savitsky D, Calame K. Savitsky D, et al. J Exp Med. 2006 Oct 2;203(10):2305-14. doi: 10.1084/jem.20060411. Epub 2006 Sep 5. J Exp Med. 2006. PMID: 16954370 Free PMC article.
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