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Tumor suppressor Foxo3a is involved in the regulation of lipopolysaccharide-induced interleukin-8 in intestinal HT-29 cells.
Snoeks L, Weber CR, Turner JR, Bhattacharyya M, Wasland K, Savkovic SD. Snoeks L, et al. Infect Immun. 2008 Oct;76(10):4677-85. doi: 10.1128/IAI.00227-08. Epub 2008 Aug 4. Infect Immun. 2008. PMID: 18678662 Free PMC article.
Mouse model of enteropathogenic Escherichia coli infection.
Savkovic SD, Villanueva J, Turner JR, Matkowskyj KA, Hecht G. Savkovic SD, et al. Infect Immun. 2005 Feb;73(2):1161-70. doi: 10.1128/IAI.73.2.1161-1170.2005. Infect Immun. 2005. PMID: 15664959 Free PMC article.
Differing roles of protein kinase C-zeta in disruption of tight junction barrier by enteropathogenic and enterohemorrhagic Escherichia coli.
Tomson FL, Koutsouris A, Viswanathan VK, Turner JR, Savkovic SD, Hecht G. Tomson FL, et al. Gastroenterology. 2004 Sep;127(3):859-69. doi: 10.1053/j.gastro.2004.06.014. Gastroenterology. 2004. PMID: 15362041
FOXO3 growth inhibition of colonic cells is dependent on intraepithelial lipid droplet density.
Qi W, Fitchev PS, Cornwell ML, Greenberg J, Cabe M, Weber CR, Roy HK, Crawford SE, Savkovic SD. Qi W, et al. J Biol Chem. 2013 Jun 7;288(23):16274-81. doi: 10.1074/jbc.M113.470617. Epub 2013 Apr 18. J Biol Chem. 2013. PMID: 23603907 Free PMC article.
Reduced mitochondrial activity in colonocytes facilitates AMPK╬▒2-dependent inflammation.
Heller S, Penrose HM, Cable C, Biswas D, Nakhoul H, Baddoo M, Flemington E, Crawford SE, Savkovic SD. Heller S, et al. Among authors: savkovic sd. FASEB J. 2017 May;31(5):2013-2025. doi: 10.1096/fj.201600976R. Epub 2017 Feb 9. FASEB J. 2017. PMID: 28183804 Free PMC article.
EPEC-activated ERK1/2 participate in inflammatory response but not tight junction barrier disruption.
Savkovic SD, Ramaswamy A, Koutsouris A, Hecht G. Savkovic SD, et al. Am J Physiol Gastrointest Liver Physiol. 2001 Oct;281(4):G890-8. doi: 10.1152/ajpgi.2001.281.4.G890. Am J Physiol Gastrointest Liver Physiol. 2001. PMID: 11557508
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