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The cancer biomarker problem.
Sawyers CL. Sawyers CL. Nature. 2008 Apr 3;452(7187):548-52. doi: 10.1038/nature06913. Nature. 2008. PMID: 18385728 Review.
Role for c-Abl tyrosine kinase in growth arrest response to DNA damage.
Yuan ZM, Huang Y, Whang Y, Sawyers C, Weichselbaum R, Kharbanda S, Kufe D. Yuan ZM, et al. Among authors: sawyers c. Nature. 1996 Jul 18;382(6588):272-4. doi: 10.1038/382272a0. Nature. 1996. PMID: 8717045
Progression of metastatic human prostate cancer to androgen independence in immunodeficient SCID mice.
Klein KA, Reiter RE, Redula J, Moradi H, Zhu XL, Brothman AR, Lamb DJ, Marcelli M, Belldegrun A, Witte ON, Sawyers CL. Klein KA, et al. Among authors: sawyers cl. Nat Med. 1997 Apr;3(4):402-8. doi: 10.1038/nm0497-402. Nat Med. 1997. PMID: 9095173
A mechanism for hormone-independent prostate cancer through modulation of androgen receptor signaling by the HER-2/neu tyrosine kinase.
Craft N, Shostak Y, Carey M, Sawyers CL. Craft N, et al. Among authors: sawyers cl. Nat Med. 1999 Mar;5(3):280-5. doi: 10.1038/6495. Nat Med. 1999. PMID: 10086382
The phosphatidylinositol 3-Kinase AKT pathway in human cancer.
Vivanco I, Sawyers CL. Vivanco I, et al. Among authors: sawyers cl. Nat Rev Cancer. 2002 Jul;2(7):489-501. doi: 10.1038/nrc839. Nat Rev Cancer. 2002. PMID: 12094235 Review. No abstract available.
Survival signaling mediated by c-Jun NH(2)-terminal kinase in transformed B lymphoblasts.
Hess P, Pihan G, Sawyers CL, Flavell RA, Davis RJ. Hess P, et al. Among authors: sawyers cl. Nat Genet. 2002 Sep;32(1):201-5. doi: 10.1038/ng946. Epub 2002 Aug 5. Nat Genet. 2002. PMID: 12161751
TORward AKTually useful mouse models.
Mellinghoff IK, Sawyers CL. Mellinghoff IK, et al. Among authors: sawyers cl. Nat Med. 2004 Jun;10(6):579-80. doi: 10.1038/nm0604-579. Nat Med. 2004. PMID: 15170198 No abstract available.
Targeted cancer therapy.
Sawyers C. Sawyers C. Nature. 2004 Nov 18;432(7015):294-7. doi: 10.1038/nature03095. Nature. 2004. PMID: 15549090 Review.
Cross-species comparisons of cancer signaling.
Graeber TG, Sawyers CL. Graeber TG, et al. Among authors: sawyers cl. Nat Genet. 2005 Jan;37(1):7-8. doi: 10.1038/ng0105-7. Nat Genet. 2005. PMID: 15624012 No abstract available.
Transcriptional regulation of a metastasis suppressor gene by Tip60 and beta-catenin complexes.
Kim JH, Kim B, Cai L, Choi HJ, Ohgi KA, Tran C, Chen C, Chung CH, Huber O, Rose DW, Sawyers CL, Rosenfeld MG, Baek SH. Kim JH, et al. Among authors: sawyers cl. Nature. 2005 Apr 14;434(7035):921-6. doi: 10.1038/nature03452. Nature. 2005. PMID: 15829968
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