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Role for c-Abl tyrosine kinase in growth arrest response to DNA damage.
Yuan ZM, Huang Y, Whang Y, Sawyers C, Weichselbaum R, Kharbanda S, Kufe D. Yuan ZM, et al. Nature. 1996 Jul 18;382(6588):272-4. doi: 10.1038/382272a0. Nature. 1996. PMID: 8717045
Identification of the JNK signaling pathway as a functional target of the tumor suppressor PTEN.
Vivanco I, Palaskas N, Tran C, Finn SP, Getz G, Kennedy NJ, Jiao J, Rose J, Xie W, Loda M, Golub T, Mellinghoff IK, Davis RJ, Wu H, Sawyers CL. Vivanco I, et al. Cancer Cell. 2007 Jun;11(6):555-69. doi: 10.1016/j.ccr.2007.04.021. Cancer Cell. 2007. PMID: 17560336
Will kinase inhibitors have a dark side?
Sawyers CL. Sawyers CL. N Engl J Med. 2006 Jul 20;355(3):313-5. doi: 10.1056/NEJMcibr062354. N Engl J Med. 2006. PMID: 16855275 No abstract available.
Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors.
Mellinghoff IK, Wang MY, Vivanco I, Haas-Kogan DA, Zhu S, Dia EQ, Lu KV, Yoshimoto K, Huang JH, Chute DJ, Riggs BL, Horvath S, Liau LM, Cavenee WK, Rao PN, Beroukhim R, Peck TC, Lee JC, Sellers WR, Stokoe D, Prados M, Cloughesy TF, Sawyers CL, Mischel PS. Mellinghoff IK, et al. N Engl J Med. 2005 Nov 10;353(19):2012-24. doi: 10.1056/NEJMoa051918. N Engl J Med. 2005. PMID: 16282176
Antibody-based profiling of the phosphoinositide 3-kinase pathway in clinical prostate cancer.
Thomas GV, Horvath S, Smith BL, Crosby K, Lebel LA, Schrage M, Said J, De Kernion J, Reiter RE, Sawyers CL. Thomas GV, et al. Clin Cancer Res. 2004 Dec 15;10(24):8351-6. doi: 10.1158/1078-0432.CCR-04-0130. Clin Cancer Res. 2004. PMID: 15623612
Will mTOR inhibitors make it as cancer drugs?
Sawyers CL. Sawyers CL. Cancer Cell. 2003 Nov;4(5):343-8. doi: 10.1016/s1535-6108(03)00275-7. Cancer Cell. 2003. PMID: 14667501 Review. No abstract available.
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