Saxena K - Search Results

1

Chemical Proteomics and Structural Biology Define EPHA2 Inhibition by Clinical Kinase Drugs.

Heinzlmeir S, Kudlinzki D, Sreeramulu S, Klaeger S, Gande SL, Linhard V, Wilhelm M, Qiao H, Helm D, Ruprecht B, Saxena K, Médard G, Schwalbe H, Kuster B. Heinzlmeir S, et al. Among authors: saxena k. ACS Chem Biol. 2016 Dec 16;11(12):3400-3411. doi: 10.1021/acschembio.6b00709. Epub 2016 Nov 7. ACS Chem Biol. 2016. PMID: 27768280

2

NMR backbone assignment of a protein kinase catalytic domain by a combination of several approaches: application to the catalytic subunit of cAMP-dependent protein kinase.

Langer T, Vogtherr M, Elshorst B, Betz M, Schieborr U, Saxena K, Schwalbe H. Langer T, et al. Among authors: saxena k. Chembiochem. 2004 Nov 5;5(11):1508-16. doi: 10.1002/cbic.200400129. Chembiochem. 2004. PMID: 15481030

3

How much NMR data is required to determine a protein-ligand complex structure?

Schieborr U, Vogtherr M, Elshorst B, Betz M, Grimme S, Pescatore B, Langer T, Saxena K, Schwalbe H. Schieborr U, et al. Among authors: saxena k. Chembiochem. 2005 Oct;6(10):1891-8. doi: 10.1002/cbic.200500092. Chembiochem. 2005. PMID: 16013076

4

Folding and activity of cAMP-dependent protein kinase mutants.

Langer T, Sreeramulu S, Vogtherr M, Elshorst B, Betz M, Schieborr U, Saxena K, Schwalbe H. Langer T, et al. Among authors: saxena k. FEBS Lett. 2005 Aug 1;579(19):4049-54. doi: 10.1016/j.febslet.2005.06.015. FEBS Lett. 2005. PMID: 16026785 Free article.

5

1H, 13C and 15N backbone resonance assignment of the Hsp90 binding domain of human Cdc37.

Sreeramulu S, Kumar J, Richter C, Vogtherr M, Saxena K, Langer T, Schwalbe H. Sreeramulu S, et al. Among authors: saxena k. J Biomol NMR. 2005 Jul;32(3):262. doi: 10.1007/s10858-005-8530-7. J Biomol NMR. 2005. PMID: 16132836 No abstract available.

6

Discovery of Mycobacterium tuberculosis protein tyrosine phosphatase A (MptpA) inhibitors based on natural products and a fragment-based approach.

Manger M, Scheck M, Prinz H, von Kries JP, Langer T, Saxena K, Schwalbe H, Fürstner A, Rademann J, Waldmann H. Manger M, et al. Among authors: saxena k. Chembiochem. 2005 Oct;6(10):1749-53. doi: 10.1002/cbic.200500171. Chembiochem. 2005. PMID: 16196020 No abstract available.

7

NMR characterization of kinase p38 dynamics in free and ligand-bound forms.

Vogtherr M, Saxena K, Hoelder S, Grimme S, Betz M, Schieborr U, Pescatore B, Robin M, Delarbre L, Langer T, Wendt KU, Schwalbe H. Vogtherr M, et al. Among authors: saxena k. Angew Chem Int Ed Engl. 2006 Jan 30;45(6):993-7. doi: 10.1002/anie.200502770. Angew Chem Int Ed Engl. 2006. PMID: 16374788 No abstract available.

8

Biomolecular NMR: a chaperone to drug discovery.

Betz M, Saxena K, Schwalbe H. Betz M, et al. Among authors: saxena k. Curr Opin Chem Biol. 2006 Jun;10(3):219-25. doi: 10.1016/j.cbpa.2006.04.006. Epub 2006 May 5. Curr Opin Chem Biol. 2006. PMID: 16679046 Free PMC article. Review.

9

NMR backbone assignment of the N-terminal domain of human HSP90.

Jacobs DM, Langer T, Elshorst B, Saxena K, Fiebig KM, Vogtherr M, Schwalbe H. Jacobs DM, et al. Among authors: saxena k. J Biomol NMR. 2006;36 Suppl 1:52. doi: 10.1007/s10858-006-9030-0. Epub 2006 Jul 5. J Biomol NMR. 2006. PMID: 16821127 No abstract available.

10

Discovery of a new class of inhibitors of Mycobacterium tuberculosis protein tyrosine phosphatase B by biology-oriented synthesis.

Nören-Müller A, Wilk W, Saxena K, Schwalbe H, Kaiser M, Waldmann H. Nören-Müller A, et al. Among authors: saxena k. Angew Chem Int Ed Engl. 2008;47(32):5973-7. doi: 10.1002/anie.200801566. Angew Chem Int Ed Engl. 2008. PMID: 18604796 No abstract available.

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