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Estrogen receptor-α is required for the osteogenic response to mechanical loading in a ligand-independent manner involving its activation function 1 but not 2.
Windahl SH, Saxon L, Börjesson AE, Lagerquist MK, Frenkel B, Henning P, Lerner UH, Galea GL, Meakin LB, Engdahl C, Sjögren K, Antal MC, Krust A, Chambon P, Lanyon LE, Price JS, Ohlsson C. Windahl SH, et al. Among authors: saxon l. J Bone Miner Res. 2013 Feb;28(2):291-301. doi: 10.1002/jbmr.1754. J Bone Miner Res. 2013. PMID: 22972752 Free PMC article.
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