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mTOR Signaling in Growth, Metabolism, and Disease.
Saxton RA, Sabatini DM. Saxton RA, et al. Cell. 2017 Apr 6;169(2):361-371. doi: 10.1016/j.cell.2017.03.035. Cell. 2017. PMID: 28388417 Free article. No abstract available.
Structural basis for leucine sensing by the Sestrin2-mTORC1 pathway.
Saxton RA, Knockenhauer KE, Wolfson RL, Chantranupong L, Pacold ME, Wang T, Schwartz TU, Sabatini DM. Saxton RA, et al. Science. 2016 Jan 1;351(6268):53-8. doi: 10.1126/science.aad2087. Epub 2015 Nov 19. Science. 2016. PMID: 26586190 Free PMC article.
SAMTOR is an S-adenosylmethionine sensor for the mTORC1 pathway.
Gu X, Orozco JM, Saxton RA, Condon KJ, Liu GY, Krawczyk PA, Scaria SM, Harper JW, Gygi SP, Sabatini DM. Gu X, et al. Among authors: saxton ra. Science. 2017 Nov 10;358(6364):813-818. doi: 10.1126/science.aao3265. Science. 2017. PMID: 29123071 Free PMC article.
The CASTOR Proteins Are Arginine Sensors for the mTORC1 Pathway.
Chantranupong L, Scaria SM, Saxton RA, Gygi MP, Shen K, Wyant GA, Wang T, Harper JW, Gygi SP, Sabatini DM. Chantranupong L, et al. Among authors: saxton ra. Cell. 2016 Mar 24;165(1):153-164. doi: 10.1016/j.cell.2016.02.035. Epub 2016 Mar 10. Cell. 2016. PMID: 26972053 Free PMC article.
Mechanism of arginine sensing by CASTOR1 upstream of mTORC1.
Saxton RA, Chantranupong L, Knockenhauer KE, Schwartz TU, Sabatini DM. Saxton RA, et al. Nature. 2016 Aug 11;536(7615):229-33. doi: 10.1038/nature19079. Epub 2016 Aug 3. Nature. 2016. PMID: 27487210 Free PMC article.
15 results