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Genome instability in progeria: when repair gets old.
Misteli T, Scaffidi P. Misteli T, et al. Nat Med. 2005 Jul;11(7):718-9. doi: 10.1038/nm0705-718. Nat Med. 2005. PMID: 16015360 No abstract available.
Release of chromatin protein HMGB1 by necrotic cells triggers inflammation.
Scaffidi P, Misteli T, Bianchi ME. Scaffidi P, et al. Nature. 2002 Jul 11;418(6894):191-5. doi: 10.1038/nature00858. Nature. 2002. PMID: 12110890
In vitro generation of human cells with cancer stem cell properties.
Scaffidi P, Misteli T. Scaffidi P, et al. Nat Cell Biol. 2011 Aug 21;13(9):1051-61. doi: 10.1038/ncb2308. Nat Cell Biol. 2011. PMID: 21857669 Free PMC article.
Transformation resistance in a premature aging disorder identifies a tumor-protective function of BRD4.
Fernandez P, Scaffidi P, Markert E, Lee JH, Rane S, Misteli T. Fernandez P, et al. Among authors: scaffidi p. Cell Rep. 2014 Oct 9;9(1):248-260. doi: 10.1016/j.celrep.2014.08.069. Epub 2014 Oct 2. Cell Rep. 2014. PMID: 25284786 Free PMC article.
Distinct structural and mechanical properties of the nuclear lamina in Hutchinson-Gilford progeria syndrome.
Dahl KN, Scaffidi P, Islam MF, Yodh AG, Wilson KL, Misteli T. Dahl KN, et al. Proc Natl Acad Sci U S A. 2006 Jul 5;103(27):10271-10276. doi: 10.1073/pnas.0601058103. Epub 2006 Jun 26. Proc Natl Acad Sci U S A. 2006. PMID: 16801550 Free PMC article.
Lamin A-dependent nuclear defects in human aging.
Scaffidi P, Misteli T. Scaffidi P, et al. Science. 2006 May 19;312(5776):1059-63. doi: 10.1126/science.1127168. Epub 2006 Apr 27. Science. 2006. PMID: 16645051 Free PMC article.
The cell nucleus and aging: tantalizing clues and hopeful promises.
Scaffidi P, Gordon L, Misteli T. Scaffidi P, et al. PLoS Biol. 2005 Nov;3(11):e395. doi: 10.1371/journal.pbio.0030395. Epub 2005 Nov 15. PLoS Biol. 2005. PMID: 16277559 Free PMC article.
Good news in the nuclear envelope: loss of lamin A might be a gain.
Scaffidi P, Misteli T. Scaffidi P, et al. J Clin Invest. 2006 Mar;116(3):632-4. doi: 10.1172/JCI27820. J Clin Invest. 2006. PMID: 16511598 Free PMC article. Review.
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